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Outside-In signaling of soluble and solid-phase fibrinogen through integrin alp…

Tohyama(Y),Tohyama(K),Tsubokawa(M),Asahi(M),… Blood 1998-09-10

...Syk was tyrosine-phosphorylated but FAK was dephosphorylated, whereas solid-phase fibrinogen promptly caused tyrosine ph...

Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in a…

Lanier(L L),Corliss(B C),Wu(J),Leong(C),Phil… Nature 1998-03-02

...Syk protein tyrosine kinases, suggesting that the activation pathway is similar to that of the T- and B-cell antigen rec...

The role of CD45 and CD45-associated molecules in T cell activation.

Altin(J G),Sloan(E K) Immunol Cell Biol 1998-02-09

...Syk family, and with numerous proteins of 29-34 kDa. These CD45-associated molecules may play an important role in regul...

Physical and functional association of Fc alpha R with protein tyrosine kinase …

Gulle(H),Samstag(A),Eibl(M M),Wolf(H M) Blood 1998-02-11

...Syk did not result in upregulation of Syk activity. Despite the lack of enhanced Syk kinase activity, downstream signali...

Antibodies directed against ZAP-70 cross-react with a 66 kDa tyrosine kinase in…

Yoneya(H),Yanagi(S),Inatome(R),Ding(J),Hitom… Biochem Biophys Res Commun 1998-05-14

...Syk family tyrosine kinases which plays an essential role in growth, differentiation, and function of T lymphocytes. In ...

Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk ty…

Deckert(M),Elly(C),Altman(A),Liu(Y C) J Biol Chem 1998-05-14

...Syk (Syk and Zap-70) family protein tyrosine kinases (PTKs) which, in turn, phosphorylate multiple intracellular substra...

Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene acti…

Deckert(M),Tartare-Deckert(S),Hernandez(J),R… Immunity 1998-12-31

...Syk kinases, Ras, and calcineurin. Thus, 3BP2 is an important adaptor that may couple activated Zap-70/Syk to a LAT-cont...

Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine resid…

Feshchenko(E A),Langdon(W Y),Tsygankov(A Y) J Biol Chem 1998-05-07

...Syk-related protein-tyrosine kinases, Fyn, Yes, and Syk appear to play a major role in phosphorylation of c-Cbl, whereas...

Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-…

Fluckiger(A C),Li(Z),Kato(R M),Wahl(M I),Och… EMBO J 1998-06-01

...Syk dramatically reduced the initial phase calcium response, demonstrating that Btk/Tec and Syk family kinases may exert...

IgA Fc receptor (CD89) activation enables coupling to syk and Btk tyrosine kina…

Launay(P),Lehuen(A),Kawakami(T),Blank(U),Mon… J Leukoc Biol 1998-05-20

...syk, and Bruton tyrosine kinase (Btk). Syk was found to be associated with Fc alphaR and its phosphorylation was increas...

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