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Downstream signals initiated in mast cells by Fc epsilon RI and other receptors.

Beaven(M A),Baumgartner(R A) Curr Opin Immunol 1997-02-10

...Syk in a vaccinia expression system and Syk-negative variants of rat basophilic (RBL-2H3) cells. These studies demonstra...

Collagen-stimulated activation of Syk but not c-Src is severely compromised in …

Ichinohe(T),Takayama(H),Ezumi(Y),Arai(M),Yam… J Biol Chem 1997-02-18

...Syk tyrosine kinases suggested a potential role for GPVI in regulating protein-tyrosine phosphorylation by collagen (Ich...

SLP-76 is a substrate of the high affinity IgE receptor-stimulated protein tyro…

Hendricks-Taylor(L R),Motto(D G),Zhang(J),Si… J Biol Chem 1997-02-12

...Syk activity but is not dependent on Ca+2 mobilization. These data, together with our previous work documenting its role...

Structural aspects of signal transduction in B-cells.

Vihinen(M),Smith(C I) Crit Rev Immunol 1997-02-21

...Syk, are activated to transmit the signal further. In this review the signaling events are discussed in structural terms...

Impaired tyrosine phosphorylation and Ca2+ mobilization, but not degranulation,…

Nishizumi(H),Yamamoto(T) J Immunol 1997-03-11

...Syk kinase. In this work, using primary mast cells derived from wild-type (lyn +/+) and lyn-deficient (lyn -/-) mice, we...

Increased secretion of TNF-alpha by costimulation of mast cells via CD28 and Fc…

Tashiro(M),Kawakami(Y),Abe(R),Han(W),Hata(D)… J Immunol 1997-03-11

...Syk, c-Cbl, Shc, and Vav. CD28-stimulated tyrosine phosphorylation was followed by a rebound hypophosphorylation. Intere...

Functional and physical interactions of Syk family kinases with the Vav proto-o…

Deckert(M),Tartare-Deckert(S),Couture(C),Mus… Immunity 1997-01-30

...Syk, the SH2 domain of Vav, and tyrosine residues in the linker domain of Syk. Vav also associated with Syk and Zap in a...

Syk, but not Lyn, recruitment to B cell antigen receptor and activation followi…

Pao(L I),Cambier(J C) J Immunol 1997-04-02

...Syk tyrosine kinases and subsequent downstream events. CD45 expression is required for BCR triggering of certain of thes...

syk kinase activation by a src kinase-initiated activation loop phosphorylation…

El-Hillal(O),Kurosaki(T),Yamamura(H),Kinet(J… Proc Natl Acad Sci U S A 1997-04-07

...syk activation loop by both src family kinases and other molecules of activated syk, suggesting that syk activation occu...

Reconstitution of T cell antigen receptor-induced Erk2 kinase activation in Lck…

Williams(S),Couture(C),Gilman(J),Jascur(T),D… Eur J Biochem 1997-05-29

...Syk is less dependent on the Src family kinase Lck than the activation of Zap. Here we report that overexpression of Syk...

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