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Tyrosine phosphorylation and Syk activation are involved in thrombin-induced ag…

Wang(X),Yanagi(S),Yang(C),Inatome(R),Yamamur… J Biochem 1997-07-11

...Syk have been shown to play a critical role in the induction of platelet responses to thrombin stimulation. This study i...

Antigen receptor function in chronic lymphocytic leukemia B cells.

Lankester(A C),Schijndel(G M),Pakker(N G),Va… Leuk Lymphoma 1997-08-19

...syk, which is a key enzyme for the early signalling through the BCR, were found to be markedly lower in non-proliferatin...

Cross-linking of integrins induces tyrosine phosphorylation of the proto-oncoge…

Gotoh(A),Takahira(H),Geahlen(R L),Broxmeyer(… Cell Growth Differ 1997-07-22

...Syk-associated proteins, pp40, which differed from Erks, Crk, and Crkl, binds Syk through SH2 domains of Syk and is a pr...

Transphosphorylation of Bruton's tyrosine kinase on tyrosine 551 is critical fo…

Kurosaki(T),Kurosaki(M) J Biol Chem 1997-07-21

...Syk was required for tyrosine phosphorylation of Btk in BCR signaling. These results suggest that transphosphorylation o...

Genetic evidence for a tyrosine kinase cascade preceding the mitogen-activated …

Wan(Y),Bence(K),Hata(A),Kurosaki(T),Veillett… J Biol Chem 1997-07-31

...Syk to feed into the MAPK cascade in these cells. The central role of Syk is further strengthened by data showing that S...

Distinctive functions of Syk and Lyn in mediating osmotic stress- and ultraviol…

Qin(S),Minami(Y),Kurosaki(T),Yamamura(H) J Biol Chem 1997-08-18

...Syk or Lyn, functional roles of Syk and Lyn in apoptotic response elicited by cellular stress were investigated. DT40 ce...

Syk is required for BCR-mediated activation of p90Rsk, but not p70S6k, via a mi…

Li(H L),Forman(M S),Kurosaki(T),Puré(E) J Biol Chem 1997-08-18

...Syk- and DT40Lyn- B cells. The phosphorylation and activation of p90Rsk was ablated in Syk-deficient B cells but unaffec...

Evidence supporting a role for microfilaments in regulating the coupling betwee…

Pierini(L),Harris(N T),Holowka(D),Baird(B) Biochemistry 1997-07-10

...Syk. Cytochalasin D alone causes tyrosine phosphorylation of a protein at approximately 75 kDa, and it reduces hapten-in...

The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activ…

Poole(A),Gibbins(J M),Turner(M),van Vugt(M J… EMBO J 1997-07-03

...Syk. Tyrosine phosphorylation of Syk and phospholipase Cgamma2 by collagen stimulation is absent in mice lacking the Fc ...

Serine phosphorylation of Cbl induced by phorbol ester enhances its association…

Liu(Y C),Liu(Y),Elly(C),Yoshida(H),Lipkowitz… J Biol Chem 1997-05-15

...Syk family protein-tyrosine kinases caused a marked increase in the phosphotyrosine content of Cbl without a concomitant...

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