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Bacterial extract OM-85 BV protects mice against experimental chronic rhinosi...

Tao(Yanli),Yuan(Tiejun),Li(Xuechang),Yang(... Int J Clin Exp Pathol 2016-05-16

...SOCS3, tumor necrosis factor (TNF)-α, and interferon (IFN)-γ in samples were assessed by using real-time PCR (RT-PCR) an...

Suppressor of cytokine signaling 3 A+930-->G (rs4969168) polymorphism is asso...

Guo(Tao),Yin(Rui-Xing),Nie(Rong-Jun),Chen(... Int J Clin Exp Pathol 2016-05-10

This study aimed to detect the association of the suppressor of cytokine signaling 3 gene (SOCS3) A+930-->G (rs4969168) ...

Gain-of-function STAT1 mutations impair STAT3 activity in patients with chron...

Zheng(Jie),van de Veerdonk(Frank L),Crossl... Eur J Immunol 2016-01-08

...SOCS3/c-Myc) as likely underlying mechanism. STAT binding to the high affinity sis-inducible element was intact but bind...

B10 Cells Ameliorate the Progression of Lupus Nephritis by Attenuating Glomer...

Yu(Miao),Song(You),Zhu(Ming-Xin),Liang(Wei... Cell Physiol Biochem 2016-05-24

...SOCS3 expression. At the same time, the serum anti-dsDNA autoantibody, TNF-α and IFN-γ levels were also reduced, while t...

Immature B Cell Egress from Bone Marrow Is SOCS3 Independent.

Nadrah(Kristina),Beck(Thomas C),Pereira(Jo... PLoS One 2016-05-06

...SOCS3 in CXCR4 signaling in developing B cell subsets. We show that in mice conditionally deficient in SOCS3 exclusively...

Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development.

Roncero(A M),López-Nieva(P),Cobos-Fernánde... Leukemia 2016-06-01

...SOCS3 might contribute to enhance the activation of JAK-STAT signaling. Of utmost interest is that primary T-LBL samples...

Transcriptional repression of SOCS3 mediated by IL-6/STAT3 signaling via DNMT...

Huang(Li),Hu(Bin),Ni(Jianbo),Wu(Jianghong)... J Exp Clin Cancer Res 2016-10-13

...SOCS3 in pancreatic cancer.,The expression of SOCS3 and other genes in pancreatic cancer was examined by Quantitative re...

Though Active on RINm5F Insulinoma Cells and Cultured Pancreatic Islets, Reco...

Berner(Anika),Bachmann(Malte),Bender(Chris... Front Pharmacol 2016-01-21

...Socs3, Bcl3, and Reg3b. In addition, IL-22 also activates STAT1 in this cell type. To refine those observations, IL-22 b...

Suppressors of cytokine signalling in ankylosing spondylitis and their associ...

Chen(Chun-Hsiung),Chen(Hung-An),Liao(Hsien... Clin Exp Rheumatol 2016-04-29

...SOCS3 correlated with ESR (r=0.297, p=0.031) and CRP (r=0.320, p=0.019). T cells SOCS3 correlated with BASFI (r=0.337, p...

Vitamin D3 alters microglia immune activation by an IL-10 dependent SOCS3 mec...

Boontanrart(Mandy),Hall(Samuel D),Spanier(... J Neuroimmunol 2016-07-12

...SOCS3). Therefore, vitamin D3 increases the expression of IL-10 creating a feedback loop via SOCS3 that downregulates th...

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