...Syk and ZAP-70, in Fc gamma RI-mediated signaling. Cross-linking of the Fc gamma RI multimeric receptor in monocytic cel...
...Syk families. Coordinated action of these components initiates numerous intracellular events leading finally to local re...
...Syk tyrosine kinase. Using Syk-deficient mast cells we show that they fail to degranulate, synthesize leukotrienes and s...
...Syk associates preferentially with the gamma-chain subunit and not with Fc gamma RI itself. This association is dependen...
...Syk. In contrast, in a T-cell line, expression of 292F led to basal NF-AT induction independent of T-cell receptor stimu...
...Syk synergistically phosphorylate HS1, and that Tyr-378 and Tyr-397 of HS1 are the critical residues for its BCR-induced...
...Syk (scFv-Syk). In a murine T cell hybridoma, direct aggregation of chimeric Syk with antigen culminates in interleukin-...
...Syk occurs at the higher (DCT)2-cys concentrations in parallel with beta phosphorylation but does not occur in its absen...
...Syk. These findings may provide insight into the mechanisms by which the BCR, and other such multimeric receptor complex...
...Syk leads to degranulation and release of such mediators of the allergic response as histamine and serotonin. Regulation...
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