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Structural aspects of signal transduction in B-cells.

Vihinen(M),Smith(C I) Crit Rev Immunol 1997-02-21

...Syk, are activated to transmit the signal further. In this review the signaling events are discussed in structural terms...

Tyrosine phosphorylation and Syk activation are involved in thrombin-induced ag…

Wang(X),Yanagi(S),Yang(C),Inatome(R),Yamamur… J Biochem 1997-07-11

...Syk have been shown to play a critical role in the induction of platelet responses to thrombin stimulation. This study i...

Serine phosphorylation of Cbl induced by phorbol ester enhances its association…

Liu(Y C),Liu(Y),Elly(C),Yoshida(H),Lipkowitz… J Biol Chem 1997-05-15

...Syk family protein-tyrosine kinases caused a marked increase in the phosphotyrosine content of Cbl without a concomitant...

Role of tyrosine phosphorylation of HS1 in B cell antigen receptor-mediated apo…

Yamanashi(Y),Fukuda(T),Nishizumi(H),Inazu(T)… J Exp Med 1997-05-14

...Syk synergistically phosphorylate HS1, and that Tyr-378 and Tyr-397 of HS1 are the critical residues for its BCR-induced...

The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosi…

Ota(Y),Samelson(L E) Science 1997-05-02

...Syk leads to degranulation and release of such mediators of the allergic response as histamine and serotonin. Regulation...

B-cell antigen receptor-induced apoptosis requires both Ig alpha and Ig beta.

Tseng(J),Eisfelder(B J),Clark(M R) Blood 1997-04-01

...Syk. These findings may provide insight into the mechanisms by which the BCR, and other such multimeric receptor complex...

Membrane-bound ezrin is involved in B-cell receptor-mediated signaling: potenti…

Rozsnyay(Z),Sarmay(G),Zoller(M),Gergely(J) Immunol Lett 1997-06-23

...syk and induction of calcium mobilization response, suggests that ezrin might be implicated in the regulation of transme...

IgE receptor (Fc epsilon RI) and signal transduction.

Kinet(J P),Jouvin(M H),Paolini(R),Numerof(R)… Eur Respir J Suppl 1997-01-22

...syk (probably via its SH2 domains) as well as other signalling molecules. Syk kinase would then be activated by the enga...

Coupling of the IL2 receptor complex with non-receptor protein tyrosine kinases.

Miyazaki(T),Taniguchi(T) Cancer Surv 1997-02-11

...Syk PTKs. The recruited PTKs are then activated following ligand stimulation to invoke intracellular signalling for the ...

Platelet activation and signal transduction by convulxin, a C-type lectin from …

Polgár(J),Clemetson(J M),Kehrel(B E),Wiedema… J Biol Chem 1997-07-02

...SYK), c-Cbl, and p36-38. However, unlike collagen, pp125(FAK) and some other bands are not tyrosine-phosphorylated. Conv...

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