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TP53 BRCA1 CRISPR single-cell cancer

Burn(T C),Connors(T D),Van Raay(T J),Dackows… Genome Res 1996-12-05

...TSC2) disease genes. An estimated 20 genes are present in this region of chromosome 16. We have initiated studies to ide...

Henske(E P),Scheithauer(B W),Short(M P),Woll… Am J Hum Genet 1996-09-25

...TSC2 tumors are more likely than TSC1 tumors to require surgical resection or that TSC2 is more common than TSC1 in our ...

Kumar(A),Kandt(R S),Wolpert(C),Roses(A D),Pe… Hum Mol Genet 1996-07-08

...TSC2). The TSC2 gene has been isolated. To date, only a small number of intragenic deletional and point mutations have b...

Maheshwar(M M),Sandford(R),Nellist(M),Cheadl… Hum Mol Genet 1996-10-22

Germ-line mutations of the TSC2 tumour suppressor gene have been identified in humans with tuberous sclerosis and in the...

Vrtel(R),Verhoef(S),Bouman(K),Maheshwar(M M)… J Med Genet 1996-12-05

...TSC2, on chromosome 16p13.3. Clinical criteria for diagnosis have been established, but diagnosis of patients with minim...

Jin(F),Wienecke(R),Xiao(G H),Maize(J C),DeCl… Proc Natl Acad Sci U S A 1996-10-31

...Tsc2. Tumor cells expressing the transfected Tsc2 gene became more anchorage-dependent and lost their ability to form tu...

Xiao(G H),Jin(F),Yeung(R S) Cell Growth Differ 1996-01-25

Tuberous sclerosis 2 (Tsc2) gene is the target of a germline insertion in the Eker rat model of inherited cancer suscept...

Wienecke(R),König(A),DeClue(J E) J Biol Chem 1995-08-16

...TSC2), encodes an open reading frame with a putative protein product of 1784 amino acids. The putative TSC2 product (tub...

Xiao(G H),Jin(F),Yeung(R S) Oncogene 1995-08-29

...Tsc2) gene. In this study, we have identified and characterized a full-length rat intracisternal A-particle (IAP) elemen...

Short(M P),Richardson(E P),Haines(J L),Kwiat… Brain Pathol 1995-10-19

...TSC2, has been cloned, although its function remains speculative. The identification of the TSC1 gene on chromosome 9q, ...

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