...TSC2. Intriguingly, the TSC2 product, tuberin, has an area of sequence homology with the GTPase activating protein rap1G...
...Tsc2) gene is localized, was found in the renal cell carcinomas which developed from hybrid F1 rats carrying the Eker mu...
Major genes which cause tuberous sclerosis (TSC) and autosomal dominant polycystic kidney disease (ADPKD), known as TSC2...
...Tsc2 product. The present determination of the Tsc2 gene and establishment of strong conservation between the rat and ma...
...TSC2, has been cloned, although its function remains speculative. The identification of the TSC1 gene on chromosome 9q, ...
...TSC2) gene, and predisposition to tumor development is inherited in an autosomal dominant fashion. Uterine and/or cervic...
...Tsc2) gene. We now describe a germline mutation in the gene encoding Tsc2 caused by the insertion of an approximately 5 ...
...TSC2) encodes a 5.5-kb transcript that is widely expressed. The TSC2 gene product, named tuberin, is a 1784-amino-acid p...
...TSC2) gene gives rise to the dominantly inherited cancer in the Eker rat model. The function of the TSC2/Tsc2 gene produ...
...TSC2). The TSC2 gene has recently been isolated, while the TSC1 gene has been mapped to a 5-cM region between the marker...
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