...ACAT2 decreased, while the decomposition gene ACSL1 increased (p < 0.05). Western Blot further confirmed enhanced expres...
...Acat2 expression, indicating altered cholesterol handling that may limit substrate availability for BA synthesis. In con...
...ACAT2 within this pathway, while downregulating the expression of ME1. The underlying mechanism may involve the inhibiti...
...ACAT2), apovitellenin 1 (APOV1), vitellogenin 1 (VTG1), membrane-bound O-acyltransferase domain-containing protein 2 (MB...
...ACAT2. Consistent with this interaction, CS greatly downregulated the mRNA and protein expression of ACAT2 in small inte...
...ACAT2), β-sitosterol and stigmasterol significantly lowered the level of cholesterol oleate in Caco-2 cells by 57.1 ± 0....
...ACAT2, as well as the inflammatory gene IL6. 3D mouse and human liver spheroid models of MASH, characterized by elevated...
...ACAT2, and MTP, as well as reduced hepatic levels of MTP and LDLr, alongside increased levels of ABCG5/G8 and LXRα/β, in...
...ACAT2) and insulin-induced gene 1 (INSIG1), thereby enhancing the intracellular environment of KGN cells, promoting the ...
...ACAT2 in vitro and AAV-mediated knockdown of ACAT2 in vivo substantially negated the effects of hispidulin on GPX4/GSH l...
山东省济南市章丘区文博路2号
齐鲁师范学院 genelibs生信实验室
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