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Hepatic miR-126 is a potential plasma biomarker for detection of hepatitis B ...

Ghosh(Amit),Ghosh(Alip),Datta(Somenath),Da... Int J Cancer 2016-08-03

...APC2, CDKN2A, IRS1, CRKL, LIFR, EGR2) were verified. Thus, combination of circulating miR-126 + AFP is a promising nonin...

Clinical and molecular characterization of a de novo 19p13.3 microdeletion.

Palumbo(Pietro),Palumbo(Orazio),Leone(Mari... Mol Cytogenet 2016-05-30

...APC2, PLK5 and MBD3 genes as potential functional candidates for neurodevelopmental and behavioral phenotypes observed.,...

Association of aberrant DNA methylation in Apc(min/+) mice with the epithelia...

Guo(Yue),Lee(Jong Hun),Shu(Limin),Huang(Yi... Cell Biosci 2015-06-23

...APC2 (adenomatosis polyposis coli 2), SFRP2 (secreted frizzled-related protein 2), and DKK3 (dickkopf-related protein 3)...

RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized...

Brown(Nicholas G),VanderLinden(Ryan),Watso... Proc Natl Acad Sci U S A 2015-07-29

...APC2 and its RING partner APC11, which collaborates with the E2 UBCH10 (UBE2C) to ubiquitinate substrates. However, how ...

Overexpression of lipocalins and pro-inflammatory chemokines and altered meth...

Peng(Xinjian),Li(Wenping),Johnson(William ... PLoS One 2015-10-06

...APC2; the increased methylation was correlated with down-regulation of this tumor suppressor gene. Overexpression of pro...

The anaphase-promoting complex/cyclosome is an E3 ubiquitin ligase for Mdm2.

He(Yizhou),Tollini(Laura),Kim(Tae-Hyung),I... Cell Cycle 2015-01-29

...APC2 expression is frequently downregulated in human cancers; in tumor cell lines, APC2 downregulation correlates with M...

The pubic midline exposure for symphyseal open reduction and plate fixation.

Adams(Mark R),Scolaro(John A),Routt(Milton... J Orthop Traumatol 2015-06-17

...APC2 in 18, APC3 in 3, LC2 in 2, LC3 in 1 and VS in 1 patient(s) [anterior posterior compression (APC), lateral compress...

Testing models of the APC tumor suppressor/β-catenin interaction reshapes our...

Yamulla(Robert J),Kane(Eric G),Moody(Alexa... Genetics 2015-07-27

...APC2 mutant lacking all β-catenin-binding 20Rs and performing functional studies in human colon cancer cell lines and Dr...

Self-association of the APC tumor suppressor is required for the assembly, st...

Kunttas-Tatli(Ezgi),Roberts(David M),McCar... Mol Biol Cell 2015-09-28

...APC2 and plays an essential role in the assembly and stability of the destructosome that regulates β-cat degradation in ...

SNW1 enables sister chromatid cohesion by mediating the splicing of sororin a...

van der Lelij(Petra),Stocsits(Roman R),Lad... EMBO J 2015-02-10

...APC2. SNW1 depletion causes cohesion defects predominantly by reducing sororin levels, which causes destabilisation of c...

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