Lee(SK),Park(EJ),Lee(HS),Lee(YS),Kwon(J) Mol Cells 2012-07-00

...Cecr2 BRD is specific because it depends on the chromatin binding affinity of Cecr2 BRD. Small interfering RNA knockdown...

Cen(Y),Chen(Y),Li(X),Chen(X),Yu(B),Yan(M),Ya… Biomaterials 2024-07-00

...CECR2) is identified to overexpress in breast cancer patients, which can recognize v-rel avian reticuloendotheliosis vir...

Acharya(A),Järvelä(I),Hernandez(A),Rajendran… HGG Adv 2026-07-09

...CECR2-associated neurodevelopmental disorder. The consistent molecular and clinical overlap with CES supports CECR2's ro...

Lucas(SCC),Atkinson(SJ),Bamborough(P),Barnet… J Med Chem 2020-00-28

...CECR2) domains. This work concludes with the identification of (R)-55 (GSK232), a highly selective, cellularly penetrant...

Crawford(TD),Tsui(V),Flynn(EM),Wang(S),Taylo… J Med Chem 2016-00-09

...CECR2. The preference of distinct substituents for individual bromodomains provided selectivity handles useful for futur...

Tang(CL),Li(YQ),Du(XK),Fang(XX),Guang(YM),Li… Acta Pharmacol Sin 2025-05-00

...CECR2 was further verified by the structurally optimized compound LC-CE-7, which is an allosteric covalent CECR2 inhibit...

Atala(A) J Urol 2012-09-00

None

Sneddon(MS),Tsou(CJ),Fu(X),Shelat(AA),Pomera… Bioconjug Chem 2026-03-18

...CECR2. Here, we use a BZ1 analog, BZ1-THQ, to design a small-molecule NanoBRET tracer, MS-1, for assessing inhibitor fun...

Zahid(H),Costello(JP),Li(Y),Kimbrough(JR),Ac… ACS Chem Biol 2023-00-16

...CECR2 degrader, we observe that our pyrimidine-based analogues degrade endogenous CECR2 while showing a smaller effect o...

Sneddon(MS),Tsou(CJ),Fu(X),Shelat(AA),Pomera… bioRxiv 2025-11-26

...CECR2. Here, we use a BZ1 analog, BZ1-THQ, to design a small molecule NanoBRET tracer, MS-1, for assessing inhibitor fun...