...CSF1R) critical for microglial survival, promote microglial proliferation and ameliorate outcomes after ischemic stroke....
...CSF1R-related disorder (CSF1R-RD). Six symptomatic patients (mean follow-up, 6.6 years) were compared with six matched, ...
...Csf1r ΔFIRE/ΔFIRE mouse model where mice lack microglia but retain brain border-associated macrophages. Using two experi...
...CSF1R: colony stimulating factor 1 receptor; csf1r-cKO: csf1r conditional knockout; DIC: doxorubicin-induced cardiomyopa...
...CSF1R) are associated with the risk of off-target toxicity due to the depletion of macrophages in healthy tissues. Here,...
...CSF1R as possible binding sites for our compounds.
...CSF1R) point mutation enables exogenously administered microglia to robustly outcompete and replace maladaptive, pro-inf...
...CSF1R gene are associated with microglial deficiency in the brain and severe neurodegenerative disease, known as CSF1R-r...
...Csf1r haploinsufficiency to investigate changes in myeloid cells, Csf1r expression and leukaemia progression. Csf1r hapl...
...CSF1R-ALSP) is a rare, fatal, autosomal-dominant neurodegenerative disorder caused by pathogenic CSF1R variants and char...
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