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Proteomics and transcriptomics reveal molecular subtypes and biomarkers of ad...

Zhang(S),Guo(Z),Liu(Z),Pang(Z),Qi(F),Sun(H... Front Oncol None

...CTSB, GSTO1, and WDFY4 as potential biomarkers for predicting treatment responsiveness, and GOLGA1 and STIP1 as potentia...

Spatial transcriptomics revealed the regulatory role of CCN1 to microglia dis...

Bai(Z),Chang(Z),Wang(S),Zheng(J),Wu(H),Liu... Genes Dis 2026-11-00

...Ctsb) in LSR microglia, affecting microglial status. Our study reveals a region-specific NSC-microglia interaction regul...

Cathepsin B, Airway Pathogens, and Inflammation in the Lower Airways of Child...

Fought(MK),O'Connor(JB),Wagner(BD),Quinn(A... Pediatr Pulmonol 2026-08-00

...CTSB) remains incompletely defined. This cross-sectional study investigates relationships between pro-CTSB and mature CT...

CTSB promotes ferroptosis in macrophage-derived foam cells and aggravates pla...

Gong(F),Wang(X),Mo(W),Yang(L),Zhang(Z),Liu... Exp Cell Res 2026-08-14

...CTSB-driven HMOX1 upregulation promoted ferroptosis and exacerbated plaque vulnerability, whereas CTSB knockdown or phar...

CTSB-associated inflammation and macrophage interaction in heart failure foll...

Tan(L),Ding(R),Li(G),Wang(L),Lei(Y),Xiong(... Eur J Pharmacol 2026-08-28

...CTSB expression at both messenger RNA and protein levels. CTSB knockdown reproduced part of the anti-inflammatory phenot...

The Influence of Acute Cold Stress on Intestinal Health of the Juvenile Chine...

Ma(X),Shi(Q),Dong(Z),Chen(C),Zhu(J),Liu(X)... Animals (Basel) 2026-01-14

...Ctsb, Kras, Hras, Pik3ca, Bcl2l11, Gadd45a, Pmaip1, Ddit3, and Fos), and the p53 signaling pathway (Serpine1, Sesn2, Ccn...

Cathepsin B hyperactivation facilitates exosome release of CVB3 particles and...

Liang(T),Zhang(Z),Xu(L),Sun(Z),Xu(W) mBio 2026-01-14

...CTSB. Overexpression of CTSB increases viral replication. Inhibition of CTSB with CA074Me reduces virion release via res...

Balancing stability and activation: A pseudoparabolic activity spectrum guide...

Bai(C),Xu(X),Wang(X),Zhang(J),Yan(Q),Fu(Y)... J Control Release 2026-02-10

...CTSB)-cleavable doxorubicin (DOX) prodrug (D8·P, D12·P, D14·P, D16·P, and D18·P) with fatty acid (FAs) modification modu...

Nanoprodrug targeting tumor-associated intracellular bacteria enhances colore...

Yu(Y),Jin(Y),Zhou(Y),Cui(Z),Xin(Y),Liu(H),... J Control Release 2026-02-10

...CTSB)-cleavable linker (FRRG) to selectively kill intramacrophage F. nucleatum. MTCP-NPs undergo IL4 receptor-mediated e...

Design, synthesis and biological evaluation of novel pyrrolo[2,3-d]pyrimidine...

Mao(Z),Shen(C),Liang(S),Zhou(T),Li(J),Yang... Eur J Med Chem 2026-02-05

...CTSB, CTSC, CTSS, CTSH and other inflammation-related kinases. The NF-κB and p38 signaling pathways, which lie downstrea...

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