Sahile(HA),Christofferson(M),Alford(MA),Re... NPJ Antimicrob Resist 2025-08-04

...HRH1). Our findings establish BZT as a promising repurposed candidate and a lead compound for developing HRH1-targeting ...

Yao(R),Ouyang(Z),Xu(T),Zhu(Y),Tang(B),Li(J... J Alzheimers Dis 2025-10-00

...HRH1 was associated with the plasma Aβ42/Aβ40 ratio. PRS of immune-related genes correlated with AD biomarkers (NfL, pta...

Palestra(F),Memoli(G),Secondo(A),Cristinzi... Sci Rep 2025-08-30

...HRH1) and induced the expression of IL-6 mRNA, but not of TNF-α and IL-1β mRNAs. Histamine rapidly caused the production...

Kurakazu(I),Olmer(M),Swahn(H),Myers(K),Ken... J Clin Invest 2025-11-03

...HRH1 constitutive activity controls important OA-promoting mechanisms and indicate that HRH1 inverse agonists are promis...

Wang(K),Zhao(P),Zhu(X),Tang(F),Chen(H),Zha... Oncogene 2025-12-00

...HRH1) as a potential therapeutic target. Genetic silencing of HRH1 significantly inhibited GBM cell proliferation, migra...

Anvari(Sara),Vyhlidal(Carrie A),Dai(Hongyi... Am J Respir Cell Mol Biol 2016-04-07

...HRH1, and HRH4) within the histamine pathway. Chi square tests and Cochran-Armitage Trend were used to identify associat...

Wouters(Mira M),Balemans(Dafne),Van Wanroo... Gastroenterology 2016-08-08

...HRH1-mediated sensitization of TRPV1 is involved in IBS. Ebastine, an antagonist of HRH1, reduced visceral hypersensitiv...

Rozov(Stanislav V),Porkka-Heiskanen(Tarja)... PLoS One 2016-06-27

...Hrh1 or Hrh3 receptors. We assessed both diurnal and free-running locomotor activity rhythms of Hrh1-/- and Hrh3-/- mice...

Tanaka(Takuji),Kochi(Takahiro),Shirakami(Y... Cancers (Basel) 2016-02-24

...Hrh1-Hrh3 antagonists on inflammation-associated colorectal carcinogenesis. Male ICR mice were treated with azoxymethane...

Schneider(Erich H),Neumann(Detlef),Seifert... Neurosci Biobehav Rev 2015-07-15

...Hrh1(-/-)- and Hrh2(-/-)-mice is crucial, because many pharmacological agents lack the required selectivity to unequivoc...