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Receptor Contribution Reallocation After Removal of Literature-Derived Weight...

Cheung(N),Cheung(HK),Yu(YW),Tsang(YY) Cureus 2026-07-00

...HRH1, HTR2A, and HTR2C, contributing 25.7%, 21.6%, and 10.3% of pooled signal. Under uniform weighting, DRD2, DRD3, and ...

Polyphyllin II inhibits thyroid cancer progression by targeting HRH1 and supp...

Sun(J),Liang(H),Zhang(Y),Ding(D),Xiang(Q),... Oncol Rep 2026-09-00

...HRH1) was identified as a key oncogenic target that is highly expressed in thyroid cancer and contributes to malignant p...

Novel N-chloroacetyl-2-pyrazoline analogs with 2-naphthyl and ferrocenyl grou...

Veeragoni(D),Ghosh(H),Ansari(A),Bhattachar... Cancer Drug Resist None

...HRH1). In vivo antitumor efficacy was tested on HCT116 xenografts in NSG mice. Results: Compounds Clac10 and Clac12 sign...

Tape Strip Transcriptomics Reveal Nemolizumab Effects on Pruritus, Hyperplasi...

Liu(D),Duca(ED),Delaleu(N),Lau(M),Pulsinel... Allergy 2026-09-04

...HRH1, KLK6/7/9) and genes involved in epidermal hyperplasia and ECM remodeling (e.g., COL1A1/12A1, IGFBP3). Inflammatory...

A HRH1-YAP1 feedback loop drives pancreatic cancer progression and predicts t...

Chen(J),Wen(J) Oncol Lett 2026-08-00

...HRH1 stabilizes and activates YAP1 signaling, while YAP1 knockdown downregulates HRH1 transcription, potentially through...

Substance P and somatostatin neurons limit facial itch by recruiting distinct...

Wheeler(JJ),Williams(N),Vigneshwar(A),Lasc... Commun Biol 2026-05-02

...HRH1 and HRH3 are both involved in mediating mixed itch-and-pain sensations, the specific activity of Substance P (SP)- ...

Kaempferol alleviates schizophrenia-like social and cognitive deficits throug...

Li(M),Wang(B),Gao(C),Sun(J),Liu(J),Xiao(L)... Phytomedicine 2026-07-00

...Hrh1 gene in cholinergic neurons and chemogenetic inhibition of cholinergic neurons in the nucleus of the horizontal lim...

Cetirizine suppresses cancer-associated fibroblast-mediated fibrotic remodeli...

Sasaki(A),Hosonuma(M),Maruyama(Y),Funayama... Breast Cancer Res 2026-04-26

...HRH1 knockdown, supporting inverse agonist activity. Functionally, cetirizine inhibited CAF-induced migration and EMT ma...

Genetically-predicted placental gene expression links to uterine fibroids and...

Akerele(AT),Hampton(G),Kim(J),Jaworski(J),... Placenta 2026-05-22

...HRH1. Our findings demonstrate a shared genetic relationship between UFs and ENDO in the placenta. The placenta specific...

Quantitative deciphering of mammalian histamine receptors through mathematica...

Hassan(SS),Nawn(D),Goswami(P),Mukherjee(N)... Biochem Biophys Res Commun 2026-06-11

Histamine receptors (HRH1-HRH4) are G-protein coupled receptors (GPCRs) that mediate essential physiological functions, ...

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