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Differential Roles for IL-4Rα and IL-13Rα1 in Immune Cell Infiltration and Ep...

Dsilva(A),Sharma(S),Barakey(S),Wagner(A),K... Allergy 2026-06-18

...Il4i1, Ccl5, Muc4, Mmp10, Mcpt1/2, Areg, Pparg, and Tff2. The transcriptome profile of experimental EoG was markedly dis...

Integrated Analysis of Macrophage-Associated Necroptosis in Alopecia Areata.

Shang(L),Zhang(D),He(Z),Bai(Y),Tan(A),Zhuo(F) Exp Dermatol 2026-06-00

...IL4I1+ macrophages_1) showed the strongest necroptosis-related signal and was associated with enhanced macrophage-fibrob...

Metabolic checkpoint blockade of IL4I1 by ZY-MY-111 reactivates CD8+ T cell i...

Li(JF),Wang(H),Kang(L),Xu(CC),Liu(YC),Li(Z... Acta Pharmacol Sin 2026-09-00

Metabolic hijacking of tryptophan (Trp) via the IL4I1-AHR axis is a pivotal immune evasion mechanism in cancers, yet the...

Disruption of macrophage migration inhibitory factor signaling induces major ...

Klaver(D),Gander(H),Frena(B),Martin(M),Ama... Mol Biomed 2026-07-17

...IL4I1)⁺ TAM subsets observed across multiple cancers. These TAM-like macrophages exhibited a transcriptional program dri...

Stabilization of MHCII on dendritic cells via AhR-mediated blockade of protea...

Xie(H),Wu(H),Wang(J),Li(L),He(Y),Wang(Y),H... Int Immunopharmacol 2026-09-15

...IL4I1/CD83), AhR overexpression, or inhibitor (MG132/chloroquine/NH4Cl). Assessments included flow cytometry (MHCII/CD83...

SARgate: a structure-bioactivity analyser for navigating chemical space and m...

Labrano(L),Primavera(E),Rocchi(M),Massuoli... Eur J Med Chem 2026-11-05

...IL4I1 inhibitor datasets derived from public repositories, externally curated collections, and manually assembled patent...

CXCL10-LACTC1/C2 Expressing Mesenchymal Stem Cell Conditioned Medium Attenuat...

Molo(K),Ege(R),Ati̇k(K),Çıtak(E),Çulcuoğlu... Inflammation 2026-05-22

...IL4I1. Furthermore, conditioned medium derived from these MSCs attenuated TNF-α-induced inflammatory responses in human ...

IL4i1 activity generates oncometabolites that rescue neuroblastoma cells from...

Guyot(C),Van de Velde(LA),Kainacher(L),Ruo... Cell Rep 2026-06-23

...IL4i1, a secreted oxidoreductase, are potent suppressors of NB ferroptosis. IL4i1 metabolites (indole-3-pyruvate and 4-h...

Compensatory pathways in tryptophan metabolism and immune regulation followin...

Gontijo(I),Camurça(M),Kfoury(JR) Mol Biol Rep 2026-09-12

...IL4I1; metabolic diversion toward serotonin and melatonin pathways; microbiota-derived indole production; and cell-type-...

IL4I1 overexpression protects against nonalcoholic fatty liver disease in par...

Yang(Y),Wang(N),Chen(Y),Ma(T),Weng(M),Wu(H... J Biol Chem 2025-09-00

...IL4I1 was highly expressed in the liver of C57BL/6J mice with NAFLD induced by an 8-weeks western diet. To explore the I...

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