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Metabolomics fingerprinting identifies redox-dependent inhibition of TXNIP al...

Yadav(KS),Singh(G),Ishteyaque(S),Verma(S),... Free Radic Biol Med 2026-08-11

...NRK-52E cells exposed to high glucose (HG). Furthermore, we performed integrated high-field 800 MHz Nuclear Magnetic Res...

Discovery of 2, 4-disubstituted pyrimidine derivatives as selective HIPK2 inh...

Hu(X),Ouyang(H),Feng(C),Wu(Y),Yao(M),Xu(J)... Eur J Med Chem 2026-08-10

...NRK-49F and HK-2 cells, supporting intracellular target engagement. In TGF-β1-stimulated NRK-49F cells and HK-2 cells, b...

[Gastrointestinal metabolic surgery improves salt-sensitive hypertension via ...

Tong(D),Peng(QL),Wang(LJ),Zhao(HD),Mou(AD)... Zhonghua Xin Xue Guan Bing ... 2026-08-24

...NRK-52E cells were used. Four experimental groups were set up: high-salt group (treated with 160 mmol/L NaCl for 24 h), ...

Molecular mechanisms of podophyllotoxin-induced subacute kidney injury: Oxida...

Chen(L),Chen(Z),Li(X),Jiang(T),Zhao(H),Wan... Environ Toxicol Pharmacol 2026-09-00

...NRK-52E cells. PPT at 10 mg/kg reduced 24-h urine output (p < 0.05) and increased serum urea (p < 0.05), uric acid (p < ...

The chalcone derivative DN-053 attenuates renal fibrosis and inhibits p38 MAP...

Srichan(S),Khuituan(P),Dejyong(K),Duangtum... Biomed Pharmacother 2026-09-00

...NRK-49F renal fibroblasts, DN-053 dose-dependently inhibited TGF-β1-induced α-smooth muscle actin (α-SMA) expression wit...

Marine Bromophenols from Laminaria hyperborea&#x27;s Epiphytic Biomass: Chemical P...

Barouti(A),Ba(VL),Herfindal(L),Jordheim(M) Mar Drugs 2026-01-21

...NRK and H9c2) and in zebrafish larvae, it showed moderate toxicity at higher concentrations, indicating a reasonable sel...

Iron-quercetin complex ameliorates chronic kidney disease via inhibiting the ...

Li(J),Zhang(L),Li(Q),Zou(Y),Ni(Y),Kantapan... Tissue Cell 2026-06-00

...NRK-49F) and renal tubular cells (TCMK1) to dissect the cellular signaling. Furthermore, to elucidate the potential mech...

Shen-Shuai-II-Recipe suppresses hypoxia-induced oxidative stress and ferropto...

Xu(Y),Wang(M),Wang(L),Zhang(X),Chen(G),Wan... J Ethnopharmacol 2026-02-10

...NRK-52E cells underwent chronic hypoxia induction and were treated with SSR-medicated serum and (or) Nrf2 inhibitor (ML3...

Discovery of XRF-1021, a 2,4-disubstituted-5-fluoropyrimidine derivative as a...

Hu(X),Wang(S),Fu(S),Zeng(J),Wu(Y),Gong(L),... Eur J Med Chem 2026-01-15

...NRK-49F and HK-2 cells, including Fibronectin, Collagen I and α-SMA. In vivo, 7a significantly improved renal function i...

A Novel lncRNA MSTRG.16386.1 as ceRNA Promotes Kidney Injury Induced by Deep ...

Zhao(J),Xu(Y),Gao(Y),Yan(T),Meng(S),Hong(T... FASEB J 2026-01-15

...NRK-52E cell apoptosis, which was suppressed by the interaction with miR-466b-5p. In addition, we demonstrated that Spry...

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