...NRK-49F cell proliferation. Integrated network pharmacology analysis and molecular docking studies further suggested tha...
...NRK-52E). Assays included biophysical target engagement (MST, CETSA, DARTS); biochemical analyses (ubiquitination, cyclo...
...NRK-52E) were intervened with calcium oxalate monohydrate (COM) crystals and treated with agonists or inhibitors of CaSR...
...NRK-52E cells were used to evaluate the renoprotective effects of LCZ696. Renal function, histopathology, and fibrosis w...
...NRK-52E cells treated with oxalate and CDCA, indicating that CDCA may promote kidney stone formation by inhibiting CAT. ...
...NRK-52E) model. Finally, a DKD rat model was established to confirm the therapeutic efficacy in vivo and to mechanistica...
...NRK-52E cells, we conducted a targeted pharmacological screening of mechanosensitive receptor modulators, identifying tr...
...NRK-52e cells. Interestingly, the dextro-isomers [(+)-4 and (+)-5] showed more prominent activities than laevo-isomers [...
...NRK-49F cells. UUO-induced renal fibrosis in mice and TGF-β1-stimulated NRK-49F fibroblasts were used to assess the anti...
...NRK-52E cells to further elucidate the regulatory role of NOX4 in Cd-mediated nephrotoxicity. Cd exposure caused signifi...
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