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Sex Differences in Dietary-Induced Liver Steatosis and Insulin Receptor-Relat...

Cespuglio(R),Zabegalov(K),de Munter(JPM),G... Int J Mol Sci 2026-03-20

...Ptpn1, Cyp4a14, Acsl1, and Pten showed differential expression between male and female SERT-KO mice fed WD. Several diff...

GADD45A may be a potential biomarker associated with endoplasmic reticulum st...

Wang(H),Zou(J),Li(H),Jiang(G) Biochem Biophys Rep 2026-09-00

...PTPN1 genes were screened by using Lasso, SVM-RFE, and RF. Further, CCND1, GADD45A, and TRAM2 were validated as signific...

PTPN1 and PTPN2 cooperatively set interferon responsiveness thresholds that g...

Poirier(AJ),Feng(CH),Walback(E),Su(R),Hinc... Proc Natl Acad Sci U S A 2026-08-18

...PTPN1 and PTPN2 as cooperative regulators of tumor immune resistance. Dual genetic ablation of PTPN1/2 in cancer cells e...

Movement smoothness and plasma proteomics are associated with functional impa...

Gawelowicz(K),Simonsen(MB),Hedström(M),Bro... Osteoarthr Cartil Open 2026-09-00

...PTPN1, PRTFDC1, ST1A1). All downregulated proteins correlated positively with 30STS performance (|r| = 0.37-0.57), and t...

Dietary eriodictyol ameliorates hyperglycemia and multi-organ damage in strep...

Deng(X),Zheng(J),Xiao(C) J Sci Food Agric 2026-08-25

...Ptpn1, Pten, Socs3). In the liver, it shifted metabolism from gluconeogenesis (G6pc, Pck1) toward glycolysis (Gck, Pklr)...

Network pharmacology and computational-based approaches to activate NRF2 path...

Malakar(V),Dhanabal(SP),Roy(D),Malakar(CC)... Comput Biol Med 2026-03-00

...PTPN1 were identified as critical nodes associated with regulation of Nrf2 signalling involving Keap1 and GSK-3β in the ...

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 ...

Zhang(C),Jiang(Y),Liu(J),Zhang(W),Qi(J),We... Oncol Rep 2026-03-00

...PTPN1/AKT1 pathway in HCC development. Taken together, the present findings revealed a new HMBOX1/PTPN1/AKT1 axis that i...

Pro-inflammatory cytokines as regulators of protein tyrosine phosphatases and...

Stein(V),Geserick(P),Friedrich(K),Brinschw... Cell Signal 2025-11-00

...PTPN1/PTP1B) and type 2 (PTPN2/TCPTP) were evaluated after cytokine stimulation and addressed by pharmacological inhibit...

miRNA-125b-5p-rich exosomes derived from fibro-adipogenic progenitors promoti...

Yang(MM),Luo(JY),Cai(J),Qian(J),Zhu(XY),Zo... Stem Cell Res Ther 2025-07-15

...PTPN1. Furthermore, miR-125b-5p inhibited the activation of ERK pathway through inhibiting the expression of PTPN1. Over...

Unraveling genetic predisposition and oxidative stress in vitiligo developmen...

Kocić(H),Lotti(T),Jevtović-Stoimenov(T),Wo... J Med Biochem 2025-07-04

...PTPN1, PTPN22, NLRP1, FASLG, and TYR. These genes influence the immune response and melanocyte function, with the transc...

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