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Spatial inhibition of RhoA by RhoGAP15B promotes protrusive activity during c...

Yang(V),Marchant(C),Liu(B),Osswald(M),Lope... J Cell Biol 2026-06-01

...Rac1, and Cdc42 are well-established regulators of collective migration by driving the formation of cellular protrusions...

Active Rac1-Mediated Bone Marrow Retention Enhances CD33 CAR-T Cell Efficacy ...

Wang(S),Li(L),Xing(H),Xu(Y),Yan(Z),Ma(H),Y... FASEB J 2026-04-30

...Rac1 (Rac1V12). Our results demonstrated that active Rac1 enhanced the migration of T cells and CD33 CAR-T cells and pro...

Hyaluronic acid-CD44 signaling defines therapeutic resistance and immunosuppr...

Zhao(J),Ji(C),Sun(J),Tian(C),Cai(T),Wang(Z... J Immunother Cancer 2026-03-09

...RAC1-SMAD3 signaling pathway and thereby establishing an immunosuppressive microenvironment. Importantly, pharmacologica...

CSDE1 Drives Glycolysis and the Progression of Prostate Cancer Through RAC1-D...

Yin(Z),Wang(Z),Gong(W),Wang(Z),Li(Z),Xu(L)... FASEB J 2026-03-31

...RAC1 expression and RAC1-related signaling markers, accompanied by changes in MAPK pathway phosphorylation. Genetic modu...

The Biological Significance of Calmodulin Binding to Lipids.

O'Day(DH) Biology (Basel) 2026-02-28

...Rac1, RalA, and KRAS4b is covered, emphasizing its importance in protein translocation from the cell membrane to the cyt...

Sidaxue ameliorates rheumatoid arthritis by inhibiting synovial neutrophil mi...

Xu(B),Liu(S),Chen(M),Li(X),Bi(X),Xue(X),Ch... Phytomedicine 2026-05-00

...RAC1/PAK1 pathway as central to neutrophil migration in RA. MR analysis nominated PAK1 as a potential drug target. We id...

Dietary energy levels regulate feed intake of broilers through the brain-gut ...

Yang(Y),Zhou(L),Liu(H),Huang(Z),Zhang(J),L... Front Vet Sci None

...Rac1/PI3K/SF1 pathway, upregulating phosphorylated proteins and SF1 expression in the ventromedial hypothalamus. Importa...

Rac1 Constrains Memory Consolidation.

Borges(GF),Moura(BDNP),Monteiro(TA),Radisk... eNeuro 2026-04-00

...Rac1) is a small GTPase that regulates actin cytoskeleton dynamics and synaptic plasticity. Rac1 has been implicated in ...

Syntaphilin inhibits glioma invasion via modulating mitochondria redistributi...

Tian(H),Chen(X),Si(M),Xu(W) Gene 2026-06-05

...Rac1/Cdc42 expression. These findings establish SNPH as a novel diagnostic/prognostic biomarker and metastasis suppresso...

Fructose-1,6-bisphosphate couples glycolytic activity to cell adhesion.

Hoffmann(L),Duchmann(M),Lazarow(K),Huang(Y... Nat Cell Biol 2026-04-00

...Rac1 inhibitor RCC2 and a concomitant elevation of Rac1 activity resulting in actin reorganization, increased FA assembl...

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