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Wu(MC),Hsiao(CT),Chiang(WY),Yu(HW),Chen(YQ... Biomaterials 2027-01-00

...Rac1, thereby attenuating lamellipodia formation, cytoskeletal tension, and pro-osteogenic signaling. Genetic deletion o...

Liaci(C),Savarese(B),Ferretti(E),Urenda(JP... bioRxiv 2026-03-18

...RAC1/CDC42 guanine nucleotide exchange factor linked to X-linked intellectual disability (XLID46) and previously studied...

Pinilla-Macua(I),Mukerji(R),Cohen(F),Sorki... Proc Natl Acad Sci U S A 2026-03-31

...Rac1 activation and EGFR-dependent cell migration, both of which were suppressed.

Gomez-Larrauri(A),Benito-Vicente(A),Uribe(... Biomedicines 2026-03-10

...Rac1, and Janus kinase-2 (JAK2)/signal transducer and activator of transcription 3 (STAT3). These findings may contribut...

Xiong(W),Miao(D),Hou(Z),Zhang(X),Xiong(Z) Biomedicines 2026-03-10

...Rac1 and Cdc42 are the most well-studied. Rho-associated coiled coil forming protein kinase (ROCK) is the most well-rese...

Silva-de-Barros(AOD),Alves(TR),Ribeiro-Fer... Int J Mol Sci 2026-03-11

...RAC1/3, RHOA/C, WDR1, FSCN1) and glycolytic enzymes (ENO1, ALDOA, PKM, LDHA), alongside the suppression of integrin- and...

Li(L),Zhang(X),Tang(G),Wu(J),Huang(Q) Pharmaceuticals (Basel) 2026-03-12

...Rac1, RhoA, Cdc42) and suppression of F-actin reorganization. Conclusions: This study provides, for the first time, evid...

Yun(SY),Lee(S) Am J Physiol Cell Physiol 2026-05-01

...Rac1-dependent actin remodeling without affecting Akt signaling. Collectively, these results identify NEGR1 as a critica...

Zhang(H),Lyu(H),Gong(Q),Wang(C),Wang(Q),Wa... Commun Biol 2026-03-29

...RAC1 and PARP1, are targets for potential drug repurposing. This study provides new evidence for the role of immune-medi...

Fei(Q),Li(C),Zhan(L),Li(X),Hui(Y),Jin(Y),Z... Adv Sci (Weinh) 2026-07-00

...RAC1-CDC42 signaling cascade activates, driving extensive cytoskeletal rearrangement and enhancing the migratory and inv...