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XRASGRP2 is essential for blood vessel formation during Xenopus development.

Suzuki(Kan),Takahashi(Shuji),Haramoto(Yosh... Int J Dev Biol 2010-07-08

...RASGRP2, which is the Xenopus ortholog of mammalian RASGRP2. XRASGRP2 over-expression induced ectopic vascular formation...

CalDAG-GEFI and platelet activation.

Stefanini(Lucia),Bergmeier(Wolfgang) Platelets 2010-08-12

...RasGRP2) at the nexus of the rapid Ca(2+)-dependent platelet activation, (b) demonstrated a complex synergy between sign...

Identification of the gene regulatory region in human rasgrp2 gene in vascula...

Nagamine(Kentaro),Matsuda(Akira),Hori(Taka... Biol Pharm Bull 2010-11-26

...RASGRP2) is a calcium- and diacylglycerol-responsive guanine nucleotide exchange factor. Previously, we reported that XR...

Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affectin...

Svensson(Lena),Howarth(Kimberley),McDowall... Nat Med 2009-03-30

...RASGRP2) specifying the CALDAG-GEF1 protein, but we show that this change is not responsible for the LAD-III disorder. I...

Unbiased screening for transcriptional targets of ZKSCAN3 identifies integrin...

Yang(Lin),Zhang(Li),Wu(Qiuyu),Boyd(Douglas D) J Biol Chem 2009-02-19

...RasGRP2, insulin-like growth factor-2, integrin beta 4), cell migration (MST1R), angiogenesis (vascular endothelial grow...

XRASGRP2 expression during early development of Xenopus embryos.

Nagamine(Kentaro),Matsuda(Akira),Asashima(... Biochem Biophys Res Commun 2008-07-24

...RASGRP2. In the present study, we analyzed the expression pattern of xrasgrp2 during Xenopus embryogenesis. The xrasgrp2...

Hypoxia and estrogen co-operate to regulate gene expression in T-47D human br...

Seifeddine(Ramzi),Dreiem(Anne),Tomkiewicz(... J Steroid Biochem Mol Biol 2007-08-23

...RasGRP2 and transferrin (TF) an antagonistic interaction was noted. The results demonstrate that hypoxic conditions and ...

Differential membrane binding and diacylglycerol recognition by C1 domains of...

Johnson(Joanne E),Goulding(Rebecca E),Ding... Biochem J 2007-09-04

...RasGRP2, RasGRP4alpha and RasGRP4beta. Sequence alignments indicate that all RasGRP C1 domains have the potential to bin...

Regulation of Ras in lymphocytes: get a GRP.

Stone(J C) Biochem Soc Trans 2007-01-29

...RasGRP2 acts on the Ras-related protein Rap and functions in platelet adhesion. RasGRP4 is expressed in mast cells and c...

Gene profiling involved in immature CD4+ T lymphocyte responsible for systemi...

Deng(Y J),Huang(Z X),Zhou(C J),Wang(J W),Y... Mol Immunol 2006-04-25

...RASGRP2 and ARL5 might be responsible for the abnormal development of CD4+ T cells of SLE; (3) HIG2, TCF7, KHSRP, WWP1, ...

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