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A novel G13-RAPGEF2-RAP1 signaling pathway critical for platelet adhesion and...

Paul(DS),Rocco(DJ),Clark(EG),Schug(WJ),Mar... Blood 2026-06-18

...RASGRP2) is the highest expressed and functionally dominant platelet RAP-GEF. However, a genome-wide association study a...

ATF3 Modulates the Endoplasmic Reticulum Stress-Induced Impairment of Milk Sy...

Zhang(C),Dai(W),Liu(Y),Xu(H),Liu(H) Int J Mol Sci 2026-05-10

...RASGRP2, PRKACB, MAP3K5, and DUSP10 confirmed as direct transcriptional targets of ATF3, mediating its regulation of the...

[Allogeneic hematopoietic stem cell transplantation for RASGRP2 gene-related ...

Wang(CL),Meng(LH),Xia(W),Long(SQ),Fang(CY)... Zhonghua Xue Ye Xue Za Zhi 2026-04-14

This study retrospectively analyzed a 4-year-and-8-month-old boy with RASGRP2-associated inherited platelet function dis...

Identification of an immunogenic epitope from RASGRP2 with specificity for HL...

Li(V),Pandey(K),Binder(MD),Reid(HH),Lim(JJ... J Neuroimmunol 2026-09-00

...RASGRP2 epitope(s) that could be used to develop tolerogenic therapies. RASGRP2-derived peptides of varying DR15 binding...

PBMC DEG/miRNA biomarkers of TDP-43 pathology in ALS.

Manchinu(MF),Congiu(M),Massidda(M),Borgher... Neurobiol Dis 2026-08-00

...Rasgrp2, were consistently dysregulated across central and peripheral tissues in the TDP-43 rat model. RT-qPCR analysis ...

Multi-omics Mendelian randomization integrating metabolism, microbiome and im...

Shi(S),Song(W),Wu(Z),Cheng(Y),Liu(H),Tian(... Front Endocrinol (Lausanne) None

...RASGRP2-was prioritized, showed structured correlations with B-cell, NK-cell and CD4+ memory T-cell subsets, and showed ...

APOA1, DEFB103A_DEFB103B and DSG3 Are Novel Circulating Biomarkers of Psoriasis.

Dźwigała(M),Sys(D),Życka-Krzesińska(J),Ryb... Int J Mol Sci 2026-06-26

...RASGRP2, MAP2K6, LXN, NBEAL2, and VPS54) in psoriasis requires further studies.

Novel/Recurrent Variants in Pakistani Glanzmann Thrombasthenia and Glanzmann-...

Shakoor(M),Amar(A),Farhan(S),Hameed(A),Nav... Thromb Haemost 2026-07-30

...RASGRP2- and FERMT3-mediated platelet intracellular signaling, respectively. While globally rare, prevalence of these bl...

Identification of novel RASGRP2 mutations in patients with platelet dysfunction.

Broojerdi(MH),Tabibian(S),Shabestari(RM),B... Transfus Apher Sci 2025-08-00

...RASGRP2 mutation. The RASGRP2 gene encodes calcium- and DAG-regulated guanine exchange factor-1 (CalDAG-GEFI), which pla...

Targeting FCRLA to induce necrosis in lung adenocarcinoma: a novel strategy f...

Sun(X),Cai(B),Zhang(S),Cao(X),Wang(Z),Cai(... Front Immunol 2025-00-00

...RASGRP2, CD79A, and FCRLA) were further screened. CD79A and FCRLA were significantly expressed in the LUAD group, wherea...

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