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Regulatory interplay of miR-361-5p/TWIST1/SOX4 axis modulating epithelial-mesen…

Zhao(S),Shen(M),Li(X),Zhao(Z),Liao(J),Luo(L) Int J Biol Macromol 2026-07-20

...SOX4 via TWIST1 and formed a negative feedback loop with SOX4, reinforcing the suppression of metastasis. This TWIST1/SO...

The castration-resistant prostate cancer-associated SNP rs11067228 facilitates …

Jiang(Y),Zhao(Z),Li(P),Su(G),Qian(Y),Zhao(Y)… Int J Biol Sci None

...SOX4, activating candidate target gene expression. Taken together, our findings indicated that the rs11067228-associated...

SOX4-Mediated Post-transcriptional Suppression of PTEN via miR-106b∼25 Cluster …

Sun(F),Gao(L),Wang(M),Liu(P),Wang(B),Hu(J),W… Mol Cancer Res 2026-01-02

...SOX4 expression is increased in patients with prostate cancer with low PTEN levels, and the expression of SOX4 and PTEN ...

SOX4-STAT6-MTHFD2 axis drives hepatocellular carcinoma progression and treatmen…

Tsai(CL),Yu(MC),Hsu(CL),Tang(HY),Lee(YS),Chi… Cell Death Dis 2026-01-03

...SOX4 in HCC cells. Genetic ablation or knockdown of SOX4 induced hypermethylation of the STAT6 promoter, suppressing its...

Integrated multiomics analysis reveals the molecular features and crucial regul…

Zhang(K),Zhang(LY),Qin(X),Zhang(YW),Xie(WJ),… Commun Biol 2026-01-08

...SOX4 is directly associated with the promoters of WNT1 and WNT3A. Interestingly, increased autophagy regulates the expre...

The long noncoding RNA AC093895.1 promotes ovarian cancer formation and metasta…

Huang(B),An(H),Qiu(Y),Ni(Z),Chen(L),Lin(J),L… Cell Death Dis 2026-02-03

...SOX4 could bind to the AC093895.1 promoter, forming a positive feedback loop SOX4/AC093895.1/miR-1253/SOX4. Therapeutic ...

TGFβ signaling promotes cell cycle progression and resistance to the CDK4/6 inh…

Ali(MM),Itoh(Y),Badji(AMP),Gallant(S),Tsirig… Cell Death Dis 2026-02-04

...SOX4 binding motifs in oncogenic cells. Transcriptomic analyses unexpectedly revealed the upregulation of DNA replicatio...

CITED2 deficiency drives pulmonary hypoplasia via miR-200b and inflammatory pat…

Jank(M),Kuna(M),Wang(J),Schwartz(J),Miyake(Y… J Pediatr Surg 2026-06-00

...Sox4, Sox11, and Sox12 downregulated in a rat nitrofen model of CDH, but Sox4 and Sox11 upregulated in CITED2-deficient ...

Single-cell multiomic analysis of mesenchymal cells reveals molecular signature…

Lu(L),McLinden(AP),Walker(NM),Vittal(R),Wang… JCI Insight 2026-07-08

...SOX4, and FOXP2 were identified as putative regulators of this state with substantial overlap in predicted targets. Targ...

CircRPPH1 promotes hepatocellular carcinoma progression through inhibiting PPAR…

Ru(W),Lu(Y),Gan(L),Yao(S),Wan(H),Nie(F),Di(S… Cell Mol Life Sci 2026-04-30

...SOX4, which inhibited the transcription of PPARα. CircRPPH1 could also competitively bind with USP1, resulting in increa...

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