Cavka(L),Nandakumar(S),Wu(Q),Mehta(NJ),Ozay(… Eur Urol 2026-05-13

...SPOP mutations, and RB1 alterations. IDH1 mutations were associated with global transcriptional repression and evidence ...

Makovec(A),Gustafson(AP),Gandhi(N),Rampalli(… Clin Cancer Res 2026-08-03

...SPOP, FOXA1, and TMPRSS2:ERG fusions), and actionable surface antigens (TROP2 and NECTIN-4). Weak correlations were foun...

Park(SK),Lee(J),Park(SJ),Kim(YN),Shin(GH),Da… Proc Natl Acad Sci U S A 2026-05-12

...SPOP) is a typical example, exhibiting tumor-suppressing or tumor-promoting effects in different tumor types in accordan...

Olivares-Huerta(O),Castro-Coyotl(DM),Crisant… Cureus 2026-04-00

Nabais Sá-de Vries syndrome (NSDVS) is a rare disease caused by a heterozygous mutation in the SPOP gene (17q21), which ...

Bakhoum(SF),Laughney(AM) Cancer Cell 2026-02-09

...SPOP-USP7-TREX1 axis that controls cytosolic DNA clearance after DNA damage, thereby gating tumor-cell-intrinsic cyclic ...

Park(JJ),Howard(LE),Fragkogianni(S),George(D… Clin Genitourin Cancer 2026-03-00

...SPOP-mutated (SPOPmut) patients matched to 223 SPOP wild-type (SPOPwt) patients who received first-line ARPI therapy in ...

Yan(P),Xue(X),Hou(T),Wang(J),Jiang(W),Wang(Z… Biochim Biophys Acta Rev Canc… 2026-04-00

...SPOP's tumor suppressor functions and structural features, upstream regulatory mechanisms, and SPOP-targeting therapeuti...

Xiong(X),Zhu(W),Huang(W),Zhang(S),Deng(Q),Ya… MedComm (2020) 2026-08-00

...SPOP, and CHD1 are significantly less frequent. Notably, the prevailing focus on hereditary EOPC has inadvertently led t...

Li(D),Zhang(Y),Liu(Y),Zhang(Z),Qu(Y),Li(J),J… Nat Commun 2026-05-20

...SPOP F102C as oncogenic drivers. By combining interpretable AI with mechanistic insight, MetaESI establishes a methodolo...

Lu(D),Okun(S),Zhang(T),Gazzo(A),Kang(A),Nage… NPJ Precis Oncol 2026-05-20

...SPOP and MGA, both antagonists of MYC activity. SPOP- and MGA-mutant clones exhibited higher MYC levels and transcriptom...