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Reprogramming gut microenvironment for the treatment of acute severe ulcerati...

Deng(Q),Liu(J),Shen(J),Yang(S),Zhao(X),Wan... Nat Commun 2026-05-13

...SUMO1 modification at lysine 305, which promotes its compartmentalization within phase-separated structures, thereby ser...

ETS1 targets the SENP2/HSPA8/FUNDC1 axis to ameliorate bronchopulmonary dyspl...

Yang(M),Yang(Q),Meng(Y),Zhang(J),Li(S) Arch Biochem Biophys 2026-08-00

...SUMO1 modification from FUNDC1, the binding site of HSPA8 was exposed, thereby promoting the degradation of FUNDC1. In B...

SUMOylation Inhibitor TAK-981 Alleviates Hallmark Features of Preeclampsia Re...

Xiao(S),Zhang(Y),Tang(Z),Chen(C),Guo(D),Lo... Antioxidants (Basel) 2026-04-11

...SUMO1 immunoprecipitation coupled with functional validation showed that SUMOylated proteins related to oxidative stress...

Replication-competent SIVcpz CRISPR screen identifies barriers to successful ...

Xie(Q),Wang(Q),Noettger(S),Gosálbez(G),Bet... J Virol 2026-06-23

...SUMO1, and TMEM173. These hits only partially overlapped with those identified in analogous HIV-1-based screens, indicat...

SUMOylation in Neural Health and Disease: From Cellular Homeostasis to Neurod...

Oriquat(G),Jasim(IK),Gajjar(TB),Hanumantha... DNA Cell Biol 2026-07-00

...SUMO1 and the closely related SUMO2/3 isoforms. SUMOylation is a dynamic posttranslational modification that regulates p...

Exon-skipping antisense oligonucleotides targeting SUMO1 and SUMO2 demonstrat...

Garcia-Morin(A),Orozco-Sepulveda(R),Juarez... Res Sq 2026-05-05

...SUMO1IN, targeting the pre-mRNAs of SUMO2 and SUMO1, respectively, and tested them in A549 and HCC827 cell lines. While ...

Curcumin attenuates α-synuclein pathology in Parkinson's disease model mice t...

Li(Y),Zhu(Z),Zhang(K) Front Neurosci None

...SUMO1, SAE2, UBC9, PIAS1/2), and ubiquitin. Striatal dopamine levels were measured by HPLC. Curcumin treatment ameliorat...

Time-resolved mapping in calves reveals bovine herpesvirus 1 shift from mucos...

Wang(Y),Jin(H),Wang(F),Cheng(J),Cao(M),Zho... Microbiol Spectr 2026-07-23

...SUMO1-UBE2I-DAXX-SP100 core. These findings delineate the mucosal-to-neuronal trajectory, establish PML as both an effec...

Ubiquitin-mediated immunoglobulin-binding protein 1 degradation promotes auto...

Qu(X),Lv(Y),Zhang(Y),Cao(L),Zhang(J),Chen(... Andrology 2026-01-00

...SUMO1)-modified proteins and autophagy during sperm capacitation, focusing on the involvement of immunoglobulin-binding ...

Senp1 O-GlcNAcylation Promotes Mitochondrial Fragmentation by Regulating Fis1...

Guo(Z),Li(X),Chen(X),Ma(X),Yan(H) Invest Ophthalmol Vis Sci 2026-06-01

...SUMO1-ylation. Fis1 SUMO1-ylation decreased its interaction with Mfn2, which reduced the contact between mitochondria-as...

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