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SUMOylation of EphB4 enhances its stability in prostate cancer.

Maharaj(MSN),Mertens-Walker(I),Lisle(JE),H... Br J Cancer 2026-07-00

...SUMO1 modification when stimulated with ephrin-B2 ligand. SUMOylation of K616 is critical for EphB4 stability. K616R Eph...

PIAS4 inhibition induces cell cycle arrest and exhibits a synergistic effect ...

Chen(H),Hu(X),Feng(L),Cheng(X),Zhu(L),Xu(F... Oncogene 2026-05-00

...SUMO1 and SUMO2/3 modifications and identified the main SUMO2/3 modification sites. Mutations at these sites inhibit CDK...

SUMO mediates the coordinate regulation of meiotic chromosome length and cros...

Yun(Y),Qiao(H),White(M),Sandhu(S),Qiu(W),B... bioRxiv 2026-03-11

...SUMO1 results in shorter axes and longer chromatin loops. Conversely, increased SUMO1 conjugation, caused by mutation of...

Denaturing SUMO Immunoprecipitation From Mitotic Cells.

Walker(AK),Lanz(AJ),Morris(JR) Bio Protoc 2026-04-05

...SUMO1 and the almost identical SUMO2 and SUMO3 (designated SUMO2/3), are processed by an E1(SAE1:SAE2)-E2(UBC9)-E3 enzym...

Proteomic insights into the effects of cryopreservation on sperm of endangere...

Nijaran(M),Roytrakul(S),Phaonakrop(N),Thon... Reprod Biol 2026-06-00

...SUMO1) reflected activation of DNA repair and protein turnover pathways. These molecular alterations were consistent wit...

Neurokinin-1 regulates progression of triple negative breast cancer by enhanc...

Bao(L),Kong(W),Pan(X),Liu(Y),Zhang(X),Wang(J) Cell Signal 2026-08-25

...SUMO1-mediated SUMOylation at K281. Our findings demonstrate that NK-1 contributes to TNBC progression by regulating G3B...

Honokiol Suppresses Glioma Cell Proliferation by Disrupting SUMO1-YAP1 Conjug...

Sheng(Z),Fang(Q),Cui(S),Wang(J),Xiao(H),Wu... Biomolecules 2026-08-10

...SUMO1-conjugated species than in SUMO2/3-conjugated species. Through a combination of label-free proteomic screening and...

DACH1 SUMOylation protects against diabetic cardiomyopathy by suppressing end...

Lin(J),Liu(N),Li(B),Wang(Y),Li(C),Yin(Y),M... J Adv Res 2026-08-08

...SUMO1 increased DACH1 stability, helped preserve DACH1 nuclear retention, and protected cardiomyocytes from high glucose...

Protein SUMOylation confers sorafenib resistance in human hepatocellular carc...

Yuan(H),Lu(Y),Jiang(Z),Chan(YT),Wu(J),Feng... Drug Resist Updat 2026-09-00

...SUMO1 expression was significantly upregulated in resistant tumors and cell lines, and its modulation directly influence...

A Multi-omics and Machine Learning Framework Identifies Plasma SBDS as a Caus...

Cheng(P),Qiang(Y),Sun(Y),Duan(B),Ouyang(Y)... J Clin Transl Hepatol 2026-06-28

...SUMO1, Shwachman-Bodian-Diamond syndrome (SBDS), RPL7, EIF1AX, ANP32A, PCNA, FAM98A, and MPHOSPH6) achieved high diagnos...

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