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SYK-dependent lipid handling in monocyte-derived macrophages governs functional…

Zhao(Y),Hu(H),Wang(J),Hu(Y),Yang(L),Wu(Z),Zh… Brain Res Bull 2026-04-00

...SYK signaling as the critical axis governing post-SCI macrophage function. Our findings establish SYK as a therapeutic t...

Amphioxus tyrosine kinase SYK inhibits NF-κB activation through MyD88-dependent…

Xu(J),Hu(H),Lu(Q),Wei(Q),Zhang(Y),Huang(G),X… J Mol Cell Biol 2026-07-03

...SYK homolog (bjSYK) in the amphioxus Branchiostoma japonicum, a key model for understanding immune system evolution. Phy...

Interaction between NKG2D and its ligands MICA/B activates the DAP12/SYK/p53/p2…

Zhao(C),Ren(H),Ke(Q),Chen(Q),He(J),Tian(R),P… Front Immunol None

...SYK and p21. This study proposes that the NKG2D-DAP12-SYK-p53-p21 axis may represent a novel pathogenic pathway in PF, p...

Connecting Magic Dynamics in Thermofield Double States to Spectral Form Factors.

Sun(N),Zhang(P) Phys Rev Lett 2026-07-17

...SYK model, the transition occurs at a finite time, with the long-time phase marked by spontaneous Z_{2} symmetry breakin...

FLT3-SYK inhibitor and Ixazomib combination impact HOXA and oxidative stress co…

Pasupuleti(SK),Rangaraju(S),Layer(J),Padam(K… NPJ Precis Oncol 2026-02-26

...SYK, HOXA9/10, and CTNNB1 with elevated oxidative phosphorylation (OXPHOS). Proteasome inhibition induced phosphorylatio...

Treml4 Drives Microglial Activation via the Lyn/Syk/ERK Pathway in Sepsis-Assoc…

Li(R),Xie(J),Li(Q),Ouyang(Y),Zhang(Q),Wang(J… Neurochem Res 2026-05-20

...Syk and ERK. Knockout of Treml4 significantly reversed the phosphorylation of Lyn, Syk, and ERK in the hippocampus, alle...

When less is more and when it isn't: Microglial Spi1 and the limits of what we …

Koldamova(R),Fitz(NF),Lefterov(I) Neuron 2026-08-05

...Syk, Lyn, and Fcgr1, providing new insight into PU.1-dependent regulatory networks and microglial functions in neurodege...

Syk inhibition limits autoimmunity and abnormal B cell phenotype and function i…

Hornick(EL),Oxley(K),Debreceni(IL),Wieting(N… J Immunol 2026-04-15

...Syk), which is involved in multiple B cell signaling pathways. B-Traf3-/- mice treated with the Food and Drug Administra...

A ROS-responsive nanozyme delivering gallic acid synergistically ameliorates ch…

Zhou(F),Gao(S),Xiong(T),Luo(D),Lin(P),Su(J),… Int J Pharm X 2026-06-00

...Syk/NF-κB pathway and downstream inflammatory cytokines. In CRS mice, nanozyme treatment significantly alleviated nasal ...

Laminarin attenuates neuroinflammation in MPTP-induced Parkinson's disease mous…

Zhao(RY),Zhang(M),Wang(XW),Xue(F),Zheng(YY),… Inflammopharmacology 2026-04-00

...Syk and NF-κB in the substantia nigra (SN). Moreover, LAM significantly decreased the mRNA level of iNOS, TNF-α and IL-1...

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