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Early Diagnosis and Treatment of an Infant with a Novel Thyroid Hormone Recepto…

Furman(AE),Dumitrescu(AM),Refetoff(S),Weiss(… Thyroid 2021-00-00

Resistance to thyroid hormone alpha (RTHα) is caused by mutations in thyroid hormone receptor α (THRA). Little is known ...

Functional Characterization of a Novel Variant of the Thyroid Hormone Receptor …

Caron(V),Bonnycastle(K),Rio(A),Chiniara(L),H… Thyroid 2026-09-20

Resistance to thyroid hormone α (RTHα) is a rare disorder caused by pathogenic THRA variants. We investigated the molecu...

Thyroid hormone receptor alpha gene variants increase the risk of developing ob…

Fernández-Real(J M),Corella(D),Goumidi(L),Me… Int J Obes (Lond) 2014-07-16

...THRA gene sequencing of an obese woman (index case) who presented as empirical thyroid hormone receptor-α (THRA) resista...

Linkage of the nuclear hormone receptor genes NR1D2, THRB, and RARB: evidence f…

Koh(Y S),Moore(D D) Genomics 1999-05-06

The THRA gene encoding thyroid hormone receptor alpha shares an unusual partial overlap with the NR1D1 gene encoding the...

Thyroid hormone receptor-α gene knockout mice are protected from diet-induced h…

Jornayvaz(François R),Lee(Hui-Young),Jurczak… Endocrinology 2012-03-27

...Thra gene knockout (Thra-0/0) and wild-type mice using hyperinsulinemic-euglycemic clamps combined with (3)H/(14)C-label...

Common genetic variants in pituitary-thyroid axis genes and the risk of differe…

Pastor(Susana),Akdi(Abdelmounaim),González(E… Endocr Connect 2013-06-20

Thyroid hormone receptors, THRA and THRB, together with the TSH receptor, TSHR, are key regulators of thyroid function. ...

Spatiotemporal Adaptations-Driven Dynamic Thra Activation Simulates a Skin Woun…

Li(Z),Tan(J),Zhou(C),Zhou(S),Ye(Y),Li(X),She… Adv Sci (Weinh) 2025-09-00

...Thra as a key regulator of phase-coupled regeneration through two distinct yet coordinated mechanisms. In the initial ph...

Developing an l-threonine-producing strain from wild-type Escherichia coli by m…

Zhu(L),Fang(Y),Ding(Z),Zhang(S),Wang(X) Biotechnol Appl Biochem 2019-11-00

...thrA*BC-rhtC could only produce 0.68 g/L l-threonine. In addition, WMZ016/pFW01-thrA*BC-rhtC could tolerate the high con...

Cloning and characterization of the mutated threonine operon (thrA(1)5A(2)5BC) …

Sugita(T),Komatsubara(S),Kisumi(M) Gene 1988-02-04

...thrA(1)5A(2)5, thrB, and thrC genes. The thrA(1)5A(2)5 and thrC gene products were identified by the maxicell method as ...

Genomic organization of the human thyroid hormone receptor alpha (c-erbA-1) gen…

Laudet(V),Begue(A),Henry-Duthoit(C),Joubel(A… Nucleic Acids Res 1991-05-28

The thyroid hormone receptor alpha (THRA or c-erbA-1) gene belongs to a family of genes which encode nuclear receptors f...

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