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Functional Characterization of a Novel Variant of the Thyroid Hormone Receptor …

Caron(V),Bonnycastle(K),Rio(A),Chiniara(L),H… Thyroid 2026-09-20

Resistance to thyroid hormone α (RTHα) is a rare disorder caused by pathogenic THRA variants. We investigated the molecu...

Thyroid hormones drive central nervous system remodelling during flatfish metam…

Olvera(A),Carballo(C),Lazcano(I),Orozco(A),M… Mol Cell Endocrinol 2026-06-00

...thra, thrb, and mct8, underscoring the spatial complexity of endocrine regulation. These results highlight that THs are ...

Determining the Impacts of an Aquatic Copper Exposure to Ambystoma Gracile (Nor…

Danis(BEG),Su(GY),Donahue(M),Marlatt(VL) Arch Environ Contam Toxicol 2026-02-11

...thra, thrb) were unchanged. Additionally, there was no impact on the expression of an estrogen receptor (esr1α) and a de...

Single-cell atlas of hepatic cellular plasticity and immune niche reprogramming…

Zhang(Q),Zhou(N),Kan(X),Zhang(Z),Fang(Y),Liu… J Transl Med 2026-02-17

...THRA. Fibroblast-mediated intercellular communication was enhanced, especially via increased macrophage migration inhibi...

Cell composition, transcriptomic, and functional pathway changes in the hippoca…

Wang(H),Matei(E),Dou(J),Morgan(RK),Colacino(… medRxiv 2026-07-22

...THRA) and four pathways (synaptic vesicle maturation, vesicle docking) overlapped between Pb and AD. We identified overl...

A novel culture method for Rana [Lithobates] catesbeiana olfactory epithelium r…

Field(EM),Helbing(CC) Gen Comp Endocrinol 2026-08-04

...thra, thrb, and thibz. No spatial variation in hormone sensitivity within the principal cavity was observed supporting t...

The Homoserine Dehydrogenase thrA Significantly Impairs Biofilm Formation, Stre…

Luo(W),Wu(W),Zuo(Y),Zhu(J),Zhang(F),Meng(C),… Microorganisms 2026-08-09

...thrA significantly reduced biofilm formation and attenuated the adhesion and invasion of K. pneumoniae with respect to h...

Dissection of Microglial Heterogeneity and Identification of Pain-Related Subpo…

Zhao(F),Shi(J),Zhang(Y),Cao(L) Pain Res Manag 2026-00-00

...Thra among the highly ranked regulators. This study identifies the Lars2+ microglial subpopulation as a temporally dynam...

IL-33 accelerates orthodontic tooth movement by promoting M1 differentiation of…

He(Z),Tian(H),Liu(X),Duan(Y),Chen(M),Luo(Z) Sci Rep 2026-06-11

...THRA was identified as a transcriptional activator of IL-33 in hPDLFs, and its expression was also induced by orthodonti...

Epigenomic regulation of neural crest differentiation in human-induced pluripot…

Mukae(K),Shindo(M),Shi(T),Onuki(R),Yamashita… iScience 2026-06-19

...THRA1 and THRA2 isoforms) in tNCCs was associated with increased expression of MEF2C and THRA2. MEF2C and THRA2 were ass...

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