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Tumor-Derived Exosome FGD5-AS1 Promotes Angiogenesis, Vascular Permeability, an…

Liu(B),Chen(J),Shang(F),Lian(M),Shen(X),Fang… J Oncol 2022-00-00

...VAV2 axis. These results suggest that FGD5-AS1 in tumor-derived exoskeleton promotes angiogenesis, vascular permeability...

Hyperglycemic Conditions Promote Rac1-Mediated Serine536 Phosphorylation of p65…

Kowluru(A),Gamage(S),Hali(M),Gleason(N) Cell Physiol Biochem 2022-08-19

...Vav2-Rac1 (e.g., Ehop-016) signaling pathways exerted minimal effects on HG-induced p65 phosphorylation. However, EHT-18...

Determination of a prediction model for therapeutic response and prognosis base…

Lai(J),Yang(S),Chu(S),Xu(T),Huang(J) Front Genet 2022-00-00

...VAV2) was developed in the TCGA training set and validated in the TCGA testing set and GEO external validation sets. A K...

Dephosphorylation of Y228 and Y217 and phosphorylation of Y335 in p120 catenin …

Shan(B),Horton(EC),Xu(SC),Huntington(KE),Kaw… Dev Dyn 2022-00-00

...VAV2. p120 catenin serves dual roles during gastrulation of zebrafish. Phosphorylation and dephosphorylation of tyrosine...

Potentially functional genetic variants of VAV2 and PSMA4 in the immune-activat…

Bai(Y),Zheng(J),Cheng(L),Liu(Q),Zhao(G),Li(J… J Gene Med 2022-00-00

...VAV2 rs12002767 C > T, were shown to potentially affect lung cancer OS by cis-regulating the expression of the correspon...

Adherens Junction Integrity Is a Critical Determinant of Sodium Iodide Symporte…

Faria(M),Vareda(J),Miranda(M),Bugalho(MJ),Si… Cancers (Basel) 2022-10-31

...VAV2 exchange factor to activate RAC1 GTPase, inducing NIS retention at the PM, thus increasing its abundance and functi...

Cortactin: A universal host cytoskeletal target of Gram-negative and Gram-posit…

Sharafutdinov(I),Knorr(J),Rottner(K),Backert… Mol Microbiol 2022-00-00

...Vav2, and the actin-stabilizing protein CD2AP. Given that many signaling factors can affect cortactin activities, severa...

The tRNA-Cys-GCA Derived tsRNAs Suppress Tumor Progression of Gliomas via Regul…

Ren(J),Wu(X),Shang(FF),Qi(Y),Tang(Z),Wen(C),… Dis Markers 2022-00-00

...VAV2 wild-type reporter. Overexpression of tRFdb-3003a/b could down-regulated the expression levels of VAV2 protein and ...

CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reve…

Liu(X),Lu(Y),Huang(J),Xing(Y),Dai(H),Zhu(L),… Cancer Cell 2022-00-14

...VAV2-RhoA-ROCK-MLC2-MRTF-A pathway, leading to elevated contractile force and matrix production. Targeting of a Rho fami...

Regulation of bone homeostasis by MERTK and TYRO3.

Engelmann(J),Zarrer(J),Gensch(V),Riecken(K),… Nat Commun 2022-00-12

...VAV2-RHOA-ROCK axis leading to increased cell contractility and motility while TYRO3 antagonizes this effect. Consequent...

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