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Kallistatin induces breast cancer cell apoptosis and autophagy by modulating ...

Li(Pengfei),Guo(Youming),Bledsoe(Grant),Ya... Exp Cell Res 2016-08-05

...SOCS3), a tumor suppressor. Conversely, kallistatin stimulated expression of the tumorigenic suppressors miR-34a and p53...

Leptin signalling pathways in hypothalamic neurons.

Kwon(Obin),Kim(Ki Woo),Kim(Min-Seon) Cell Mol Life Sci 2016-07-28

...SOCS3, tyrosine phosphatase PTP1B, and inflammatory signaling pathways such as IKK-NFκB and JNK signaling, and ER stress...

Tetraspanin CD37 protects against the development of B cell lymphoma.

de Winde(Charlotte M),Veenbergen(Sharon),Y... J Clin Invest 2016-07-08

...SOCS3); therefore, absence of CD37 drives tumor development through constitutive activation of the IL-6 signaling pathwa...

Exposure to TiO2 Nanoparticles Induces Immunological Dysfunction in Mouse Tes...

Hong(Fashui),Wang(Yajing),Zhou(Yingjun),Zh... J Agric Food Chem 2016-08-11

...SOCS3 (-8.11 to -34.86%), and increased expression of Toll-like receptor (TLR)-3 (21.4-156.03%), TLR-4 (37.0-109.87%), n...

Suppressor of Cytokine Signaling-3 (SOCS-3) Induces Proprotein Convertase Sub...

Ruscica(Massimiliano),Ricci(Chiara),Macchi... J Biol Chem 2016-07-06

...SOCS3 in HepG2 cells (HepG2(SOCS3)) strongly inhibited STAT3 phosphorylation and induced PCSK9 mRNA and protein, with no...

Pretreatment of LPS inhibits IFN-β-induced STAT1 phosphorylation through SOCS...

Ando(Takashi),Komatsu(Takayuki),Naiki(Yosh... Biomed Pharmacother 2016-04-12

...SOCS3. The real-time PCR and immune-blot studies of SOCS3 indicated that LPS induced SOCS3 is independent of IL-6, IL-10...

A Kinetic-Model-Based Approach to Identify Malfunctioning Components in Signa...

Li(Xianhua),Ribaudo(Nicholas),Huang(Zuyi J... Biomed Res Int 2016-09-26

...SOCS3. Similarly, the TNF-α/NF-κB model was used to obtain the data in which abnormal oscillation dynamic was shown in t...

Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 an...

Kim(Min Soo),Lee(Won Sung),Jeong(Joon),Kim... Oncotarget 2016-09-20

...SOCS3-mediated JAK2 degradation, resulting in increased total JAK2 and STAT3 levels, which subsequently leads to JAK2/ST...

The early synthesis of p35 and activation of CDK5 in LPS-stimulated macrophag...

Na(Yi Rang),Jung(Daun),Gu(Gyo Jeong),Jang(... Sci Signal 2016-09-07

...SOCS3 (suppressor of cytokine signaling 3), an inhibitor of inflammatory responses in macrophages, and IL-10. Furthermor...

Restoration of skilled locomotion by sprouting corticospinal axons induced by...

Jin(Duo),Liu(Yuanyuan),Sun(Fang),Wang(Xuhu... Nat Commun 2016-05-24

...SOCS3), a negative regulator of cytokine-activated pathway, promotes sprouting of uninjured CST axons to the denervated ...

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