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Downstream signaling molecules bind to different phosphorylated immunoreceptor …

Kimura(T),Kihara(H),Bhattacharyya(S),Sakamot… J Biol Chem 1996-12-26

...Syk, Lyn, Shc, Grb2, and phospholipase C-gamma1 from lysates of rat basophilic leukemia RBL-2H3 cells. Syk was precipita...

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase …

Dikic(I),Tokiwa(G),Lev(S),Courtneidge(S A),S… Nature 1996-11-12

...Syk. Here we show that lysophosphatidic acid (LPA) and bradykinin induce tyrosine phosphorylation of Pyk2 and complex fo...

Alteration of B-cell antigen receptor signaling by CD19 co-ligation. A study wi…

Lankester(A C),Rood(P M),van Schijndel(G M),… J Biol Chem 1996-11-07

...syk. Strikingly, the assembly of Grb2 complexes that may couple the BCR to p21(ras) was clearly altered by the CD19 bisp...

Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine ki…

Latour(S),Chow(L M),Veillette(A) J Biol Chem 1996-11-07

...Syk accumulates in B-cells, mast cells, platelets, and immature T-cells. In addition, we found that an isoform of Syk (S...

The cytoplasmic tail of FcgammaRIIIAalpha is involved in signaling by the low a…

Hou(X),Dietrich(J),Geisler(N O) J Biol Chem 1996-11-07

...syk and rise in intracellular free Ca2+ following receptor ligation with specific anti-CD16 monoclonal antibody or Ig-an...

Regulation of Src family tyrosine kinase activities in adherent human neutrophi…

Yan(S R),Berton(G) J Biol Chem 1996-11-19

...syk) was not affected by catalase in normal neutrophils, and it was comparable in normal and CGD neutrophils. These find...

A novel phosphotyrosine-binding domain in the N-terminal transforming region of…

Lupher(M L),Reedquist(K A),Miyake(S),Langdon… J Biol Chem 1996-11-18

...Syk and ZAP-70 tyrosine kinases through presently undefined mechanisms. Potential Src homology 2 and 3 domain binding si...

Identification of the site in the Syk protein tyrosine kinase that binds the SH…

Couture(C),Deckert(M),Williams(S),Russo(F O)… J Biol Chem 1996-11-18

The Syk protein tyrosine kinase (PTK) is expressed in many hematopoietic cells and is involved in signaling from various...

The Syk/ZAP-70 protein tyrosine kinase connection to antigen receptor signallin…

van Oers(N S),Weiss(A) Semin Immunol 1996-01-25

...Syk/ZAP-70 family of PTKs. Following antigen-receptor stimulation, the Src-family of PTKs mediate the phosphorylation of...

Transmembrane signaling by antigen receptors of B and T lymphocytes.

DeFranco(A L) Curr Opin Cell Biol 1995-08-24

...Syk/ZAP-70 family. Recent studies have given us considerable insight into the interactions of these two types of kinases...

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