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Immature B lymphocytes are deficient in expression of the src-family kinases p5…

Wechsler(R J),Monroe(J G) J Immunol 1995-02-27

...syk, lyn, blk, hck, and fyn; in addition, we find that they express significant amounts of the src-family kinase p55fgr....

Human spleen tyrosine kinase p72Syk associates with the Src-family kinase p53/5…

Sidorenko(S P),Law(C L),Chandran(K A),Clark(… Proc Natl Acad Sci U S A 1995-02-22

...Syk and Lyn from human B lymphocytes can interact directly. Syk and Lyn coimmunoprecipitated from mature and activated B...

Tyrosine phosphorylation of Shc is mediated through Lyn and Syk in B cell recep…

Nagai(K),Takata(M),Yamamura(H),Kurosaki(T) J Biol Chem 1995-04-25

...Syk in B cells. This interaction and the requirement of Syk kinase activity for phosphorylation of Shc were also demonst...

Regulation of protein tyrosine kinases in platelets.

Clark(E A),Shattil(S J),Brugge(J S) Trends Biochem Sci 1995-03-16

...Syk and FAK, have been implicated in these phosphorylation events. These kinases are regulated by distinct receptor-medi...

Epstein-Barr virus protein LMP2A regulates reactivation from latency by negativ…

Miller(C L),Lee(J H),Kieff(E),Burkhardt(A L)… Infect Agents Dis 1995-02-03

...syk tyrosine kinases. The activity of lyn is substantially reduced. In EBV-infected cells in which LMP2A is expressed, c...

Analysis of antigen receptor signaling in B cells from mice with a retrovirus-i…

Selvey(L A),Morse(H C),June(C H),Hodes(R J) J Immunol 1995-01-19

...syk kinase, were not detected in MAIDS B cells in response to IgM cross-linking. The defect in tyrosine phosphorylation ...

N-acetyl-L-cysteine inhibits antigen-mediated Syk, but not Lyn tyrosine kinase …

Vallé(A),Kinet(J P) FEBS Lett 1995-01-23

...Syk. Here we show that the antioxidant drug N-acetyl-L-cysteine (NAC) inhibits antigen-mediated Syk activation whereas L...

src-family tyrosine kinase p55fgr is expressed in murine splenic B cells and is…

Wechsler(R J),Monroe(J G) J Immunol 1995-04-27

...Syk. Here we describe another src family kinase expressed in B cells, p55fgr. Although previous studies have suggested t...

Distinct functions of the Fc epsilon R1 gamma and beta subunits in the control …

Wilson(B S),Kapp(N),Lee(R J),Pfeiffer(J R),M… J Biol Chem 1995-03-31

...Syk and initiates a series of responses including protein-tyrosine phosphorylation, inositol 1,4,5-trisphosphate synthes...

Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from l…

Miller(C L),Burkhardt(A L),Lee(J H),Stealey(… Immunity 1995-04-26

...Syk, Pl3-K, PLC gamma 2, Vav, Shc, and MAPK. Syk, Pl3-K, PLC gamma 2, and Vav are constitutively tyrosine phosphorylated...

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