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Reconstitution of Syk function by the ZAP-70 protein tyrosine kinase.

Kong(G H),Bu(J Y),Kurosaki(T),Shaw(A S),Chan… Immunity 1995-06-22

...Syk are PTKs required for TCR and BCR function, respectively. Loss of the Syk PTK results in a nonfunctional BCR. We pro...

Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell recept…

Thome(M),Duplay(P),Guttinger(M),Acuto(O) J Exp Med 1995-06-23

...Syk and ZAP-70 after CD3 stimulation of Jurkat cells. A tyrosine-phosphorylated peptide containing the sequence predicte...

Syk is activated by phosphotyrosine-containing peptides representing the tyrosi…

Shiue(L),Zoller(M J),Brugge(J S) J Biol Chem 1995-06-05

...Syk in RBL-2H3 cell lysates and stimulated Syk kinase activity 10-fold in vitro, with half-maximal activation at 1-2 mic...

A requirement for Syk in the activation of the microtubule-associated protein k…

Hirasawa(N),Scharenberg(A),Yamamura(H),Beave… J Biol Chem 1995-06-05

...Syk and blocked by overexpression of a dominant negative form of Syk. By contrast, stimulation via the transfected, G pr...

Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig…

Rowley(R B),Burkhardt(A L),Chao(H G),Matsued… J Biol Chem 1995-06-15

...Syk activation in B cells correlates with Syk tyrosine phosphorylation as well as with Syk SH2-mediated association with...

Rapid desensitization of B-cell receptor by a dithiol-reactive protein tyrosine…

Rozsnyay(Z),Sarmay(G),Gergely(J) Immunol Lett 1995-08-03

...syk activation by H2O2, we suppose that PAO may inhibit BCR-mediated signal transduction events upstream of syk activati...

Integrin-mediated tyrosine phosphorylation and cytokine message induction in mo…

Lin(T H),Rosales(C),Mondal(K),Bolen(J B),Has… J Biol Chem 1995-08-16

...Syk. In contrast, integrin ligation with antibodies induces tyrosine phosphorylation of Syk but not of FAK or paxillin. ...

Interaction between lck and syk family tyrosine kinases in Fc gamma receptor-in…

Ting(A T),Dick(C J),Schoon(R A),Karnitz(L M)… J Biol Chem 1995-08-16

...syk family PTKs, ZAP-70, and syk. The phosphorylation of ZAP-70 and syk was enhanced markedly by overexpression of wild-...

Signal transduction by the B-cell antigen receptor.

DeFranco(A L),Richards(J D),Blum(J H),Steven… Ann N Y Acad Sci 1995-12-06

...Syk. The BCR expressed in the nonlymphoid AtT20 cells, which express the Src-family tyrosine kinase Fyn but not Syk, was...

IL-2 signaling involves recruitment and activation of multiple protein tyrosine…

Taniguchi(T),Miyazaki(T),Minami(Y),Kawahara(… Ann N Y Acad Sci 1995-12-06

...Syk PTK, and the Janus kinases, Jak1 and Jak3. cDNA expression studies revealed that the activation of these PTKs is cri...

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