...TSC2 has been shown to decrease proliferation rates of mammalian cells. Furthermore, overexpression of TSC2 has been dem...
...TSC2 mutations were identified in all cyst-positive patients who were tested (n = 8), whereas both TSC1 and TSC2 mutatio...
...TSC2 (+/+) and TSC2 (-/-) rat embryonic fibroblasts (REF) that were derived from the Eker strain.,Loss of the expression...
...TSC2, promoter methylation of TSC2, and clonality analysis. Our results document loss of the wild-type allele in six of ...
...TSC2, which encode hamartin and tuberin, respectively. The functions of these proteins have yet to be determined. Recent...
...TSC2 tumor suppressor genes. From the symptomatic resemblance among TS patients, involvement of TSC1 and TSC2 products i...
...TSC2 was studied in 20 patients with gangliogliomas. Fifteen of these tumours (75%) carried polymorphisms in the TSC2 ge...
...TSC2 E14 1516C > T 505R > X nonsense mutation was found in the SEGA. Another patient demonstrated germline mutation in T...
...TSC2 in human and rodent cells together with the finding that a homolog of TSC2 regulates the Drosophila cell cycle sugg...
...TSC2. We have characterized mutations in the Drosophila Tsc1 and Tsc2/gigas genes. Inactivating mutations in either gene...
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