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Congenital and childhood myeloproliferative disorders with eosinophilia respo...

Abraham(Shirley),Salama(Mohamed),Hancock(J... Pediatr Blood Cancer 2012-11-30

...PDGFRB) gene. Imatinib mesylate has been efficacious in treating some of these MPDs. Here we describe two patients with ...

Platelet-derived growth factors and their receptors in normal and malignant h...

Demoulin(Jean-Baptiste),Montano-Almendras(... Am J Blood Res 2012-08-23

...PDGFRB genes. Aberrant activation of PDGF receptors occurs in myeloid malignancies associated with hypereosinophilia, du...

Validation of ITD mutations in FLT3 as a therapeutic target in human acute my...

Smith(Catherine C),Wang(Qi),Chin(Chen-Shan... Nature 2012-06-25

...PDGFRB and RET; evolution of AC220-resistant substitutions at two of these amino acid positions was observed in eight of...

CD99 is a novel prognostic stromal marker in non-small cell lung cancer.

Edlund(Karolina),Lindskog(Cecilia),Saito(A... Int J Cancer 2012-12-10

...PDGFRB, PDLIM5, POSTN, SPARC, TAGLN, TNC and VCAN). The corresponding antibodies were applied on tissue microarrays, inc...

Suppression of PDGF-induced PI3 kinase activity by imatinib promotes adipogen...

Fitter(Stephen),Vandyke(Kate),Gronthos(Sta... J Mol Endocrinol 2012-07-24

...PDGFRB) is the mechanism by which imatinib promotes adipogenesis. Supporting this, functional blocking antibodies to PDG...

World Health Organization-defined eosinophilic disorders: 2012 update on diag...

Gotlib(Jason) Am J Hematol 2012-11-05

...PDGFRB, or FGFR1," chronic eosinophilic leukemia, not otherwise specified' (CEL, NOS), lymphocyte-variant hypereosinophi...

Genetic alterations activating kinase and cytokine receptor signaling in high...

Roberts(Kathryn G),Morin(Ryan D),Zhang(Jin... Cancer Cell 2012-10-25

...PDGFRB, CRLF2, and EPOR, activating mutations of IL7R and FLT3, and deletion of SH2B3, which encodes the JAK2-negative r...

Platelet-derived growth factor receptors differentially inform intertumoral a...

Kim(Youngmi),Kim(Eunhee),Wu(Qiulian),Gurya... Genes Dev 2012-08-02

...PDGFRB informed poor prognosis, while PDGFRA was a positive prognostic factor. Our results may explain mixed clinical re...

Interactions between environmental factors and polymorphisms in angiogenesis ...

Zhai(Rihong),Zhao(Yang),Liu(Geoffrey),Ter-... Cancer 2012-03-27

...PDGFRB, rs7324547 of VEGFR1, rs17619601 of VEGFR1, and rs17625898 of VEGFR1) and BMI were significantly associated with ...

Local medial microenvironment directs phenotypic modulation of smooth muscle ...

Boersema(M),Katta(K),Rienstra(H),Molema(G)... Am J Transplant 2012-10-12

...Pdgfrb was upregulated. Gene expression of Klf4 was upregulated as well, while expression of Sm22α was downregulated. Fi...

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