...TSC2. The samples consisted of 103 unique sequence heterozygotes and 126 wild-type homozygous controls.,At the temperatu...
Alterations in the rat tuberous sclerosis gene (Tsc2) are responsible for the hereditary renal carcinomas (RCs) of Eker ...
...TSC2 mutations using the protein truncation test (PTT). Three cases were predicted to be TSC2 mutations on the basis of ...
...TSC2 in 16p13.3, to be involved in the disease. The TSC2 gene, composed of 41 exons, has been isolated and is shown to e...
...Tsc2 gene mutant (Eker) rat renal carcinomas (RCs). Among them, fra-1 encoding a transcriptional factor activator protei...
...TSC2 gene, seen in both renal and central nervous system tumors from TSC patients? Second, when loss of tuberin occurs, ...
...TSC2). TSC1 markers showed different maternal and paternal haplotypes in affected children, excluding a mutation in TSC1...
...TSC2 genes, which lie close together on chromosome 16. The phenomenon of anticipation, whereby disease presentation occu...
...TSC2, and VHL genes.,Three patients (ages 7, 8, and 20 years) had renal cell carcinomas (RCCs). Two of these patients ha...
...Tsc2 and VHL genes in rats, and that 2) Tsc2 gene somatic mutation can nonetheless be one of the causes of non-Eker rat ...
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