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Loss of heterozygosity in the tuberous sclerosis gene associated regions in ade…

Suzuki(K),Ogura(T),Yokose(T),Nagai(K),Mukai(… Int J Cancer 1998-08-17

...TSC2-associated loci was observed more frequently in cases with well-differentiated adenocarcinoma (p = 0.086) and assoc...

Tctex3, related to Drosophila polycomblike, is expressed in male germ cells and…

Kawakami(S),Mitsunaga(K),Kikuti(Y Y),Ando(A)… Mamm Genome 1998-12-31

...Tsc2 gene on mouse Chromosome (Chr) 17, and HUTEX3 was located closely to HSET gene in the HLA class II region of chromo...

Hamartin, the product of the tuberous sclerosis 1 (TSC1) gene, interacts with t…

Plank(T L),Yeung(R S),Henske(E P) Cancer Res 1998-11-18

...TSC2. Tuberin, the product of TSC2, appears to be localized to the Golgi apparatus and may have a function in vesicular ...

Tuberous sclerosis-related gene expression in normal and dysplastic brain.

Vinters(H V),Kerfoot(C),Catania(M),Emelin(J … Epilepsy Res 1998-12-29

...TSC2 (on chromosome 16p13.3) encodes the protein tuberin and TSC1 (on 9q34) encodes hamartin. Tuberin has been immunoloc...

Specific induction of hepatocellular adenomas by transplacental administration …

Fukuda(T),Mitani(H),Tsutsumi(M),Konishi(Y),H… Int J Oncol 1998-12-09

...Tsc2). We document the effect of transplacental administration of N-ethyl-N-nitrosourea to Eker (Eker/+) and non-Eker (+...

LOH at 16p13 is a novel chromosomal alteration detected in benign and malignant…

Lininger(R A),Park(W S),Man(Y G),Pham(T),Mac… Hum Pathol 1998-11-05

...TSC2/PKD1 gene region (D16S423, D16S663, D16S665). LOH on chromosome 16p13 was present in 10 of 16 (63%) informative cas...

Facilitated diagnosis of the contiguous gene syndrome: tuberous sclerosis and p…

Torra(R),Badenas(C),Darnell(A),Camacho(J A),… Am J Kidney Dis 1998-07-02

...TSC2. We suggest that an additive or synergistic effect between PKD1 and TSC2 may cause this renal phenotype. A contiguo...

The genetic basis of tuberous sclerosis.

Young(J),Povey(S) Mol Med Today 1998-12-10

...TSC2, identified in 1993, and TSC1, only recently identified. Here we review the current state of knowledge of the molec...

Malignant tumors of the kidney, brain, and soft tissues in children and young a…

Al-Saleem(T),Wessner(L L),Scheithauer(B W),P… Cancer 1998-12-01

...TSC2, and VHL genes.,Three patients (ages 7, 8, and 20 years) had renal cell carcinomas (RCCs). Two of these patients ha...

The GAP-related domain of tuberin, the product of the TSC2 gene, is a target fo…

Maheshwar(M M),Cheadle(J P),Jones(A C),Myrin… Hum Mol Genet 1998-01-02

...TSC2 gene is one of two genes determining tuberous sclerosis. Inactivating germline mutations of TSC2 in patients with t...

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