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TP53 BRCA1 CRISPR single-cell cancer

Urakami(S),Tsuchiya(H),Orimoto(K),Kobayashi(… Biochem Biophys Res Commun 1998-01-15

...Tsc2 gene mutant (Eker) rat renal carcinomas (RCs). Among them, fra-1 encoding a transcriptional factor activator protei...

Au(K S),Rodriguez(J A),Finch(J L),Volcik(K A… Am J Hum Genet 1998-04-06

...TSC2), the large size of the TSC2 gene, and the variety of mutations. More than half of the mutations that we identified...

Smolarek(T A),Wessner(L L),McCormack(F X),My… Am J Hum Genet 1998-06-10

...TSC2 (chromosome 16p13) genes. TSC2 LOH was detected in seven (54%) of the angiomyolipomas. We also found TSC2 LOH in fo...

van Slegtenhorst(M),Nellist(M),Nagelkerken(B… Hum Mol Genet 1998-06-19

Tuberous sclerosis (TSC) is an autosomal dominant disorder caused by a mutation in either the TSC1 or TSC2 tumour suppre...

Fowler(L),Everitt(J),Stevens(J L),Jaken(S) Cell Growth Differ 1998-08-05

...TSC2 gene that predisposes them to renal carcinoma, whereas additional factors influence tumor promotion/progression in ...

Martignoni(G),Pea(M),Bonetti(F),Zamboni(G),C… Am J Surg Pathol 1998-06-30

...TSC2-containing region on 16p in one case, and on 3p in two cases, showing that multiple genetic alterations are taking ...

Ohno(K) No To Hattatsu 1998-04-27

Identification of NF1, TSC2 and TSC1 genes has enabled us to focus on their function and regulation. Evidence suggests t...

Mizuguchi(M),Kato(M),Yamanouchi(H),Ikeda(K),… Acta Neuropathol 1998-02-20

...TSC2 gene, in cerebral, renal and cardiac tissues obtained from patients with tuberous sclerosis and from control patien...

van Bakel(I),Sepp(T),Ward(S),Yates(J R),Gree… Hum Mol Genet 1998-02-02

...TSC2 mutations using the protein truncation test (PTT). Three cases were predicted to be TSC2 mutations on the basis of ...

Jobert(S),Bragado-Nilsson(E),Samolyk(D),Pede… Eur J Hum Genet 1998-01-21

...TSC2 in 16p13.3, to be involved in the disease. The TSC2 gene, composed of 41 exons, has been isolated and is shown to e...

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