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1-(2,3-Dibenzimidazol-2-ylpropyl)-2-methoxybenzene Is a Syk Inhibitor with Anti…

Kim(Eunji),Son(Young-Jin),Yang(Yanyan),Shen(… Molecules 0000-00-00

...Syk and its substrate, p85. Consequently, we could say that DBMB clearly suppressed the kinase activity of Syk kinase ac...

Syk kinases are required for spinal commissural axon repulsion at the midline v…

Noraz(Nelly),Jaaoini(Iness),Charoy(Camille),… Development 0000-00-00

...Syk kinases remains obscure. Previously, we identified phosphorylated forms of Syk kinases in specialized populations of...

GRID and docking analyses reveal a molecular basis for flavonoid inhibition of …

Wright(Bernice),Watson(Kimberly A),McGuffin(… J Nutr Biochem 0000-00-00

...Syk, PKC, PIM1/2, ERK, JNK and PKA. X-ray crystallographic analyses of kinase-flavonoid complexes show that flavonoid ri...

Differential Roles of the NADPH-Oxidase 1 and 2 in Platelet Activation and Thro…

Delaney(M Keegan),Kim(Kyungho),Estevez(Brian… Arterioscler Thromb Vasc Biol 0000-00-00

...Syk and phospholipase Cγ2, but minimally affected mitogen-activated protein kinase pathways. Interestingly, laser-induce...

Spleen tyrosine kinase induces MUC5AC expression in human airway epithelial cel…

Na(Hyung Gyun),Bae(Chang Hoon),Choi(Yoon Seo… Am J Rhinol Allergy 0000-00-00

...SYK induced MUC5AC expression. SYK activated significant phosphorylation of extracellular signal-related kinase (ERK)1/2...

Stability of Syk protein and mRNA in human peripheral blood basophils.

MacGlashan(Donald) J Leukoc Biol 0000-00-00

...Syk expression is 10-fold lower than most other types of leukocytes. There are indirect studies that suggest that Syk pr...

Novel SYK gene variations and changes in binding sites of miRs in breast cancer…

Faryal(R),Ishfaq(M),Hayat(T),Mahjabeen(I),Ka… Cancer Biomark 0000-00-00

...SYK gene and deregulation of SYK transcripts by miRNA in breast cancer was studied.,All exons and exon/intron boundaries...

High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells.

Kanderova(Veronika),Kuzilkova(Daniela),Stuch… Mol Cell Proteomics 0000-00-00

...SYK overexpressed in acute myeloid leukemias. In addition, OPAL1 overexpression corresponded to ETV6-RUNX1 chromosomal t...

Targeted therapies for CLL: Practical issues with the changing treatment paradi…

Jain(Nitin),O'Brien(Susan) Blood Rev 0000-00-00

...Syk inhibitors, novel anti-CD20 monoclonal antibodies such as ofatumumab and obinutuzumab, and Bcl-2 antagonists such as...

C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities …

Wang(Lan),Yin(Jie),Wang(Xuefei),Shao(Miaomia… Gastroenterology 0000-00-00

...SYK. CLEC2 and SYK interacted physically, and SYK maintained the stability of CLEC2 in cells. AGS cells with CLEC2 knock...

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