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TP53 BRCA1 CRISPR single-cell cancer

Carsillo(T),Astrinidis(A),Henske(E P) Proc Natl Acad Sci U S A 2000-06-30

...TSC2 loss of heterozygosity in 7 of 13 (54%) of angiomyolipomas from sporadic LAM patients, suggesting that LAM and TSC ...

Pasumarthi(K B),Nakajima(H),Nakajima(H O),Ji… Circ Res 2000-06-20

...TSC2-deficient cells. Surprisingly, targeted expression of the most potent TSC2 cDNA to the heart did not perturb cardia...

Mizuguchi(M),Takashima(S),Yamanouchi(H),Naka… J Neuropathol Exp Neurol 2000-04-07

...Tsc2 gene. We describe here histological and immunohistochemical findings of the brain lesions in Eker rats, with emphas...

Jónasdóttir(T J),Mellersh(C S),Moe(L),Heggeb… Proc Natl Acad Sci U S A 2000-05-17

...TSC2) and the tumor suppressor gene TP53. These data suggest that RCND may be caused by a previously unidentified tumor ...

Jónasdóttir(T J),Mellersh(C S),Moe(L),Vignau… Anim Genet 2000-07-13

The canine tuberous sclerosis 2 (TSC2) gene has been mapped to canine chromosome 6 using a canine whole genome radiation...

Mizuguchi(M),Ikeda(K),Takashima(S) Acta Neuropathol 2000-07-17

...TSC2 gene. The clinical manifestations of mutations of the two genes are hardly distinguishable, for reasons as yet unkn...

Yamasaki(S),Tanaka(S),Fujii(H),Matsumoto(T),… Histopathology 2000-06-16

...TSC2 region or 12 other chromosomal regions. The patient is free of disease over 1 year after the operation.,We consider...

Hass(J),Mayer(K),Rott(H D) Hum Mutat 2000-08-25

...TSC2. TSC1 consists of 23 exons with exon 15 being the largest one comprising 559 bp. Representing 16% of the coding reg...

Hino(O) Nihon Rinsho 2000-09-19

...TSC2) as the predisposing Eker gene. The Eker rat provides a valuable experimental model for understanding the mechanism...

Gutmann(D H),Zhang(Y),Hasbani(M J),Goldberg(… Acta Neuropathol 2000-05-23

...TSC2 on chromosome 16p. Here, we report our analysis of TSC1 (hamartin) and TSC2 (tuberin) protein expression in the cen...

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