Literature Search

Matsuda(Y),Wang(X),Oishi(H),Guan(Z),Saito(M)… Am J Transplant 2016-10-25

...Syk in development of OB, using an intrapulmonary tracheal transplant model of OB with the conditional Syk-knockout Syk(...

Zhi(Huiying),Dai(Jing),Liu(Junling),Zhu(Jieq… PLoS One 2016-05-10

...Syk were found to play key roles in IgG-induced platelet activation events. Taken together, our data suggest a complex f...

Peter(B),Winter(G E),Blatt(K),Bennett(K L),S… Leukemia 2016-07-22

...SYK was recognized by both metabolites. Together, our data show that the clinically relevant midostaurin metabolite CGP5...

Thoma(Gebhard),Veenstra(Siem),Strang(Ross),B… Bioorg Med Chem Lett 2016-06-17

...Syk inhibitor 5, which was found to be active in a rat PK/PD model. Compound 5 showed acceptable overall kinase selectiv...

Boros(Katalin),Puissant(Alexandre),Back(Morg… Oncotarget 2016-07-25

...SYK activation in primary patient samples have been lacking. In this study we quantified phosphorylated SYK (P-SYK) in A...

Uckun(Fatih M),Myers(Dorothea E),Cheng(Jianj… EBioMedicine 2016-08-15

...SYK-P-site inhibitor C61 ("C61-LNP"). C61-LNP plus low dose total body irradiation (TBI) was substantially more effectiv...

Kuiatse(Isere),Baladandayuthapani(Veerabhadr… Clin Cancer Res 2016-02-22

...Syk) is overexpressed in primary cells, suggesting that it could be a novel and rational target.,We studied the impact o...

Kim(Jung Kuk),Seo(Young-Kyo),Park(Sehoon),Pa… Biochem Cell Biol 2016-02-22

...Syk), linker for activation of T cells (LAT), and downstream MAPKs, such as ERK1/2, p38, and JNK, eventually attenuating...

Kim(Hyuk Soon),Kim(A-Ram),Kim(Do Kyun),Kim(H… Sci Signal 2016-02-04

...Syk in mast cells. Together, these findings suggest that an important function of IL-10-producing CD5(+) B cells is inhi...

Moroi(A J),Watson(S P) J Thromb Haemost 2016-02-25

...Syk tyrosine kinases, and phospholipase Cγ2. The initial events in the two signaling cascades, however, are distinct, an...