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TP53 BRCA1 CRISPR single-cell cancer

Vinters(H V),Kerfoot(C),Catania(M),Emelin(J … Epilepsy Res 1998-12-29

...TSC2 (on chromosome 16p13.3) encodes the protein tuberin and TSC1 (on 9q34) encodes hamartin. Tuberin has been immunoloc...

Fukuda(T),Mitani(H),Tsutsumi(M),Konishi(Y),H… Int J Oncol 1998-12-09

...Tsc2). We document the effect of transplacental administration of N-ethyl-N-nitrosourea to Eker (Eker/+) and non-Eker (+...

Lininger(R A),Park(W S),Man(Y G),Pham(T),Mac… Hum Pathol 1998-11-05

...TSC2/PKD1 gene region (D16S423, D16S663, D16S665). LOH on chromosome 16p13 was present in 10 of 16 (63%) informative cas...

Torra(R),Badenas(C),Darnell(A),Camacho(J A),… Am J Kidney Dis 1998-07-02

...TSC2. We suggest that an additive or synergistic effect between PKD1 and TSC2 may cause this renal phenotype. A contiguo...

Young(J),Povey(S) Mol Med Today 1998-12-10

...TSC2, identified in 1993, and TSC1, only recently identified. Here we review the current state of knowledge of the molec...

Al-Saleem(T),Wessner(L L),Scheithauer(B W),P… Cancer 1998-12-01

...TSC2, and VHL genes.,Three patients (ages 7, 8, and 20 years) had renal cell carcinomas (RCCs). Two of these patients ha...

Maheshwar(M M),Cheadle(J P),Jones(A C),Myrin… Hum Mol Genet 1998-01-02

...TSC2 gene is one of two genes determining tuberous sclerosis. Inactivating germline mutations of TSC2 in patients with t...

Yates(J R),van Bakel(I),Sepp(T),Payne(S J),W… Hum Mol Genet 1998-03-18

...TSC2). TSC1 markers showed different maternal and paternal haplotypes in affected children, excluding a mutation in TSC1...

Henske(E P),Wessner(L L),Golden(J),Scheithau… Am J Pathol 1998-01-02

...TSC2 gene, seen in both renal and central nervous system tumors from TSC patients? Second, when loss of tuberin occurs, ...

Urakami(S),Tsuchiya(H),Orimoto(K),Kobayashi(… Biochem Biophys Res Commun 1998-01-15

...Tsc2 gene mutant (Eker) rat renal carcinomas (RCs). Among them, fra-1 encoding a transcriptional factor activator protei...

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