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Inhibitory Effect of on IgE-Mediated Allergic Responses in RBL-2H3 Cells.

Yoo(Jae-Myung),Yang(Ju-Hye),Kim(Young Soo),C… Mediators Inflamm 0000-00-00

...Syk, PLC1/2, PKC, ERK, JNK, p38, and Akt. In the late phase, LPE decreased 5-lipoxygenase phosphorylation and COX-2 expr...

E2A-PBX1 Remodels Oncogenic Signaling Networks in B-cell Precursor Acute Lympho…

Duque-Afonso(Jesús),Lin(Chiou-Hong),Han(Kyuh… Cancer Res 0000-00-00

...SYK, and LCK, which encode kinases upstream of PLCγ2. Depletion of the respective upstream kinases decreased cell prolif...

Endothelial cell-derived CD95 ligand serves as a chemokine in induction of neut…

Gao(Liang),Gülcüler(Gülce Sila),Golbach(Liek… Elife 0000-00-00

...Syk-Btk/PLCγ2/Rap1 signaling that ultimately leads to integrin activation. Excitingly, CD95-deficient myeloid cells exhi...

A Tetrahydrofolate-Dependent Methyltransferase Catalyzing the Demethylation of …

Yao(Li),Yu(Lin-Lu),Zhang(Jun-Jie),Xie(Xiang-… Appl Environ Microbiol 0000-00-00

...SYK-6, respectively. The purified Dmt catalyzed the transfer of methyl from dicamba to THF to form the herbicidally inac...

The dual Syk/JAK inhibitor cerdulatinib antagonises B-cell receptor and microen…

Blunt(Matthew D),Koehrer(Stefan),Dobson(Rach… Clin Cancer Res 0000-00-00

...Syk/JAK inhibitor currently in clinical trials (NCT01994382), may improve treatment responses in patients.,PBMCs from CL...

MiR-17-92 represses PTPROt and PP2A phosphatases and amplifies tonic BCR signal…

Jablonska(Ewa),Gorniak(Patryk),Szydlowski(Ma… Exp Hematol 0000-00-00

...SYK) and AKT, critical components of BCR signal transduction in DLBCL cells. Introduction of miR-17-92 into DLBCL cells ...

Leukocyte immunoglobulin-like receptor B4 regulates key signalling molecules in…

Park(Mijeong),Raftery(Mark J),Thomas(Paul S)… Sci Rep 0000-00-00

...Syk, clathrin, E3 ubiquitin protein ligase Cbl, hepatocyte growth factor-regulated tyrosine kinase substrate, tripartite...

Integrated analysis of gene expression and methylation profiles of 48 candidate…

Li(Zibo),Heng(Jianfu),Yan(Jinhua),Guo(Xinwu)… Breast Cancer Res Treat 0000-00-00

...SYK, TGFBR2, TNFRSF10D, WIF1, and WRN) annotated with potential TFBSs in the promoter regions showed negative correlatio...

Piceatannol increases the expression of hepatocyte growth factor and IL-10 ther…

Abd-Elgawad(Hazem),Abu-Elsaad(Nashwa),El-Kar… Can J Physiol Pharmacol 0000-00-00

...Syk. This study investigates the potential ability of piceatannol to attenuate liver fibrosis and protect hepatocytes fr...

Kinases as Novel Therapeutic Targets in Asthma and Chronic Obstructive Pulmonar…

Barnes(Peter J) Pharmacol Rev 0000-00-00

...Syk-kinases, and inhaled formulations of these drugs are now in development. There has also been interest in developing ...

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