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Antitumour activity of oral E7080, a novel inhibitor of multiple tyrosine kin...

Bruheim(Skjalg),Kristian(Alexandr),Uenaka(... Int J Cancer 2011-07-27

...PDGFRB, FGFR1 or KIT on tumour cells but was significantly correlated with expression of VEGFR2 on tumour microvessels. ...

Sunitinib in advanced alveolar soft part sarcoma: evidence of a direct antitu...

Stacchiotti(S),Negri(T),Zaffaroni(N),Palas... Ann Oncol 2011-10-27

...PDGFRB. IF/confocal microscopy demonstrated coexpression and physical association between PDGFRB/vascular endothelial gr...

Array comparative genomic hybridization reveals frequent alterations of G1/S ...

Niini(Tarja),Lahti(Leo),Michelacci(Frances... Genes Chromosomes Cancer 2011-06-30

...PDGFRB was found in 8/14, 5/14, 4/14, and 4/14 cases, respectively. The regions most significantly discriminating betwee...

Characterization of NPM1-mutated AML with a history of myelodysplastic syndro...

Schnittger(S),Bacher(U),Haferlach(C),Alper... Leukemia 2011-06-09

...PDGFRB, 2 × JAK2V617F, 2 × FLT3-ITD). Backtracking of nine of these cases by quantitative real time PCR showed the NPM1m...

Cytogenetics of myeloproliferative neoplasms.

Campbell(Lynda J) Methods Mol Biol 2011-07-05

...PDGFRB, and FGFR1 genes. Mastocytosis is also included under the umbrella of MPN but the cytogenetic abnormalities obser...

Receptor tyrosine kinase and downstream signalling analysis in diffuse malign...

Perrone(Federica),Jocollè(Genny),Pennati(M... Eur J Cancer 2011-01-19

Our aim was to assess the activation profile of EGFR, PDGFRB and PDGFRA receptor tyrosine kinases (RTK) and their downst...

Changed concepts and definitions of myeloproliferative neoplasms (MPN), myelo...

Hebeda(Konnie M),Fend(F) J Hematop 2011-07-14

...PDGFRB) or fibroblast growth factor receptor 1 (FGFR1). The clinical relevance of recognising myeloid neoplasms with abe...

Proinflammatory/profibrotic effects of interleukin-17A on human proximal tubu...

Dudas(Paul L),Sague(Sarah L),Elloso(M Merl... Nephron Exp Nephrol 2011-07-22

...PDGFRB expression. Changes in ZO-1 and E-cadherin protein expression and cell morphology were examined following IL-17A ...

Screening for diverse PDGFRA or PDGFRB fusion genes is facilitated by generic...

Erben(Philipp),Gosenca(Darko),Müller(Marti... Haematologica 2011-10-05

...PDGFRB. Furthermore, significant overexpression of PDGFRB was found in a patient with an eosinophilia-associated myelopr...

Imatinib and tyrosine kinase inhibition, in the management of BCR-ABL negativ...

Mesa(Ruben A) Biologics 2011-07-14

...PDGFRb through TEL-PDGFRb) for CMML). Empiric use of imatinib in PMF has been disappointing, and in PV quite modest. Alt...

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