Literature Search

Sjölin-Goodfellow(Hanna),Frushicheva(Maria P… Sci Signal 2016-02-11

...Syk family kinase ZAP-70 (ζ chain-associated protein kinase of 70 kD) are sequentially activated in response to TCR enga...

Liang(Ming-Lu),Da(Xing-Wen),He(Ao-Di),Yao(Gu… Sci Rep 2016-04-12

...Syk, PLCγ2, Akt, GSK3β and Erk1/2. Therefore, we provide the first report to show that PMQ possesses anti-thrombotic act...

Liu(Yan),Wang(Ping),Li(Shijie),Yin(Linan),Sh… Int J Clin Exp Pathol 2016-03-29

...SYK (spleen tyrosine kinase), and PIK3R1 (phosphoinositide-3-kinase, regulatory subunit 1 (alpha)) were the common genes...

Flemming(Alexandra),Huang(Qi-Quan),Jin(Jian-… PLoS One 2016-03-15

...Syk-dependent manner, suggesting a putative role in pre-BCR signaling. To investigate this in vivo, we generated a floxe...

Nagase(Hiroshi),Kutsumura(Noriki) Arch Pharm (Weinheim) 2016-02-10

...SYK-146, called SYK-524, showed potent but non-selective agonistic activity for the opioid receptors. We also added seve...

Lu(Yue),Cai(Shuangfan),Tan(Hongsheng),Fu(Wen… Mol Cell Biochem 2016-04-25

...Syk, it directly inhibited the tyrosine kinase activity in vitro. Moreover, oral administration of OC inhibited the IgE-...

Choi(Soo-Ho),Gonen(Ayelet),Diehl(Cody J),Kim… Autophagy 2016-02-23

...SYK knockout mice, we demonstrate that SYK regulates OxLDL-induced ROS generation, MAPK8 activation, BECN1-BCL2 dissocia...

Yu(Y),Koehn(C D),Yue(Y),Li(S),Thiele(G M),He… Curr Mol Med 2016-03-24

...SYK) and the concomitant phosphorylation of mitogen-activated protein kinase kinase (MAPKK/MEK), extracellular-signal-re...

Blanco-Menéndez(Noelia),del Fresno(Carlos),F… J Immunol 2016-04-01

Dectin-1 (Clec7a) is a paradigmatic C-type lectin receptor that binds Syk through a hemITAM motif and couples sensing of...

Li(X),Kwon(O),Kim(D Y),Taketomi(Y),Murakami(… Allergy 2016-10-20

...Syk, LAT, phospholipase Cγ1, MAP kinases, the Akt/NF-κB pathway, and intracellular Ca(2+) mobilization via the activatio...