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H3K79 methylation and H3K36 trimethylation synergistically regulate gene expres…

Cooke(EW),Zeng(C),Nur(SM),Jia(Y),Huang(A),Ch… Sci Adv 2025-07-04

...TEAD4 (TEA domain transcription factor 4) and its coactivator YAP1 (Yes-associated protein 1) to these enhancers. Furthe...

Small-Molecule Covalent Stabilization and Inhibition of the TEAD·YAP1 Transcrip…

Yeh(IJ),Bum-Erdene(K),Ghozayel(MK),Gonzalez-… ACS Chem Biol 2025-09-19

...TEAD4) bind to transcriptional coactivator Yes-Associated Protein (YAP1) or its paralog transcriptional coactivator with...

Roles of ERα during mouse trophectoderm lineage differentiation: revealed by an…

Cheng(X),Xu(S),Song(C),He(L),Lian(X),Liu(Y),… Dev Growth Differ 2016-04-00

...Tead4, Gata3 and Cdx2, were significantly reduced. Overall, these results indicated that ERα might affect mouse embryo c...

CDX2 downregulation in mouse mural trophectoderm during peri-implantation is he…

Suzuki(D),Okura(K),Nagakura(S),Ogawa(H) Reprod Med Biol 2022-00-00

...TEAD4, and ESRRB. Endogenous estrogen signaling was perturbed by administrating estrogen receptor antagonist ICI 182,780...

Roles and Regulation of the Hippo Signaling Pathway in Mammalian Preimplantatio…

Sasaki(H) Cold Spring Harb Perspect Biol 2026-04-17

...TEAD4)-Yes-associated protein (YAP) control of trophectoderm (TE) and inner cell mass fate is the most extensively chara...

Cyclin K condensates bridge CDK12 to phosphorylate and drive oncogenic YAP acti…

Sun(Y),Zhang(Y),Yan(W),Duan(J),Qiao(K),Yan(G… Sci Adv 2026-07-03

...TEAD4 to stimulate YAP oncogenic activity. Coexpression of CDK12/Cyclin K and YAP predicts sensitivity to Cyclin K inhib...

The role of transcriptional coactivator TAZ in gliomas.

Li(W),Dong(S),Wei(W),Wang(G),Zhang(A),Pu(P),… Oncotarget 2016-12-13

...TEAD4. Therefore, our findings indicate that TAZ is overexpressed in glioma and translocated more into nucleus in high g...

A three-gene signature reveals changes in the tumor immune microenvironment in …

Liu(L),Tang(H),Wang(K),Liu(J),Luo(N),Jin(G) Sci Rep 2023-00-15

...TEAD4, SOCS2, CIT) was constructed, and survival analysis and receiver operating characteristic curves were drawn. The p...

A Retinoic Acid:YAP1 signaling axis controls atrial lineage commitment.

Abraham(E),Volmert(B),Roule(T),Huang(L),Yu(J… bioRxiv 2024-07-12

...TEAD4 are integrated with the atrial transcription factor enhancer network, and that YAP1 is necessary for activation of...

Butyrate stimulates the growth of human intestinal smooth muscle cells by activ…

Dai(LN),Yan(JK),Xiao(YT),Wen(J),Zhang(T),Zho… J Cell Physiol 2018-00-00

...TEAD4, CTGF, and Cyr61. These results provide evidence that Bu stimulates the growth of human intestinal muscle cells by...

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