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TP53 BRCA1 CRISPR single-cell cancer

Kobayashi(T),Mitani(H),Takahashi(R),Hirabaya… Proc Natl Acad Sci U S A 1997-05-22

We recently reported that a germ-line insertion in the rat homologue of the human tuberous sclerosis gene (TSC2) gives r...

Mizuguchi(M),Kato(M),Yamanouchi(H),Ikeda(K),… Ann Neurol 1997-02-13

...TSC2 gene product, in cerebra with or without tuberous sclerosis. Tuberin was abundant in the gray matter of normal cere...

Wolf(H K),Normann(S),Green(A J),von Bakel(I)… Acta Neuropathol 1997-04-01

...TSC2 locus in hamartomas obtained from different organs of patients with established tuberous sclerosis, including corti...

Kerfoot(C),Wienecke(R),Menchine(M),Emelin(J)… Brain Pathol 1997-03-07

...TSC2 on 16p13.3. TSC2 has been cloned, sequenced and encodes a protein (tuberin) which functions as a tumor suppressor. ...

Sepp(T),Yates(J R),Green(A J) J Med Genet 1997-03-13

...TSC2 gene on chromosome 16p13.3 and the TSC1 gene on 9q34. We now describe the spectrum of LOH in 51 TSC hamartomas from...

Au(K S),Rodriguez(J A),Rodriguez(E),Dobyns(W… Hum Mutat 1997-03-19

...TSC2). The TSC2 gene was recently cloned. We have tested 88 TSC probands with the TSC2 cDNA by Southern blotting searchi...

Aspinwall(R),Rothwell(D G),Roldan-Arjona(T),… Proc Natl Acad Sci U S A 1997-02-13

...TSC2) in chromosome region 16p13.3, we identified a gene, OCTS3, that encodes a 1-kb transcript. Analysis of OCTS3 cDNA ...

Crino(P B),Trojanowski(J Q),Dichter(M A),Ebe… Proc Natl Acad Sci U S A 1997-01-16

...TSC2) may disrupt differentiation and maturation of neuronal precursors, since the TSC2 gene product tuberin is believed...

Kobayashi(T),Urakami(S),Hirayama(Y),Yamamoto… Jpn J Cancer Res 1997-05-29

We searched for the rat homologue of the human tuberous sclerosis (TSC2) gene mutations in loss of heterozygosity (LOH)-...

Kobayashi(T),Urakami(S),Cheadle(J P),Aspinwa… Mamm Genome 1997-09-12

...Tsc2/TSC2 is conserved between the two species. Characterization of the 5' region of Tsc2 and TSC2 will facilitate studi...

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