Literature Search

Hossen(Muhammad Jahangir),Kim(Mi-Yeon),Kim(J… Am J Chin Med 2016-04-08

...Syk of NF-κB. In the present study, we explored the molecular mechanism of Pa-ME on the AP-1 activation pathway and eval...

Lovering(Frank),Aevazelis(Cristina),Chang(Je… ChemMedChem 2016-09-19

There has been significant interest in spleen tyrosine kinase (Syk) owing to its role in a number of disease states, inc...

Qiu(Qian),Yang(Chun),Xiong(Wei),Tahiri(Houda… Apoptosis 2016-07-19

...SYK expression. Perturbing SYK activity in Rb cells induced cell apoptosis and upregulated expression of p53 and p21. In...

Klokk(Tove Irene),Kavaliauskiene(Simona),San… Cell Mol Life Sci 2016-06-30

...Syk. Ricin, a protein toxin that does not cross-link surface molecules, has no effect on the same complex. Importantly, ...

Tian(Ye F),Ahn(Haelee),Schneider(Rebecca S),… Biomaterials 2016-08-22

...Syk in the upstream BCR pathway. Our integrin specific ligand functionalized 3D organoids mimic a lymphoid neoplasm-like...

Patterson(Heide Christine),Gerbeth(Carolin),… Proc Natl Acad Sci U S A 2016-02-09

...SYK (Syk), and Syk upstream of numerous targets involved in signaling, transcription, translation, metabolism, and cell ...

Karnam(Anupama),Holla(Sahana),Balaji(Kithiga… Mol Immunol 2016-01-26

...Syk pathway activates mTOR-sonic hedgehog (SHH) signaling cascade to stimulate the expression of these lipid metabolizin...

Kim(Myungsuk),Lim(Sue Ji),Lee(Hee-Ju),Nho(Ch… J Agric Food Chem 2016-05-09

...Syk, protein kinase Cμ, phospholipase Cγ, and extracellular signal-regulated kinases. CTE and aurantio-obtusin blocked m...

Choi(Jang-Sik),Hwang(Hae-Jun),Kim(Se-Won),Le… Bioorg Med Chem Lett 2016-04-20

A series of pyrazolylpyrimidine scaffold based Syk inhibitors were synthesized and evaluated for their biological activi...

Ayuso(Pedro),Plaza-Serón(María del Carmen),D… Pharmacogenet Genomics 2016-08-24

...SYK, LAT1, PLCG1, PLA2G4A, and TNFRSF11A) in 450 NIUA patients and 500 controls. We identified several statistically sig...